Example sentences for: aminoarabinose

How can you use “aminoarabinose” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, sensitivity to the antibacterial lipopeptide polymyxin B is affected by the PmrA-PmrB regulon, which mediates substitution of 4-aminoarabinose on the 4´ phosphate of lipid A [ 52 53 ] . By reducing the negative charge of lipid A, this modification decreases its electrostatic interaction with cationic peptides.

  • These alterations could result from 4-aminoarabinose substitutions on the lipid A, from other changes that reduce the number of ion-binding sites, or from changes that affect hydrophobic interactions or membrane insertion.

  • 4. This is also consistent with the suggestion, made in a recent report showing that cystic fibrosis isolates of P. aeruginosa had lipid A isoforms derivatized with aminoarabinose (or palmitate), that these structural modifications could enhance resistance to cationic antimicrobial peptides [ 61 ] . Although the acyl chains of lipid A might also provide alternative binding sites for protegrin, the orientation of lipid A on the HPA sensor chip ("butter-side down") probably removes them from consideration, at least under our study conditions.


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