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Example sentences for: alterations

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In addition, the increase in K i was identical to the increase in K d that has been observed for [ 3H]granisetron binding on this mutant [ 24 ] . Alterations in K i resulting from the W89Y mutation were slightly less, however the change was again the same for lerisetron, analog 1 and analog 2. These data suggest that all three compounds form binding site interactions with W89.
Altogether, these data suggest that the biochemical alterations of the recombinant IL-1Ra do not significantly affect its ability to antagonize the responses of synovial fibroblasts to human IL-1β.
(2) Alterations in gastric motility : ileus or diarrhea (3-5 stools per day ≥ 2 days).
The observed GC activity excess suggests that LIF and LIFR are integral to GC regulation, but that the relationship is complex and that alterations in GC response are likely to result from altered balance of the GC response cascade induced both by gain and loss of LIFR function.
1%) were guanosine at this position in the splice sequence making it likely that exon 68 will be aberrantly spliced [ 23 ] . When these two fragments were run on the DHPLC system at the lower second pass temperatures indicated in Additional file A: Primer sequences and DHPLC temperatures Excel spreadsheet, the alterations were detected (Figure 2cand 2b).