Words similar to als
Example sentences for: als
How can you use “als” in a sentence? Here are some example sentences to help you improve your vocabulary:
- ALS : Anterolateral system
The primary antibody was diluted in PBS + 0,1% Triton or optionally in addition with the previously used serum (dilutions: α-ARD, α-ALS, α-Dα2 1:10-1:100; α-RDL 1:200; α-GABA 1:500).
1 and 1q12, respectively [ 8 ] . These loci overlap with the genomic regions containing the genes for amyotrophic lateral sclerosis 5 (ALS5) and limb girdle muscular dystrophy 1B (LGMD1B), respectively [ 22 23 ] . We characterized these tropomodulin genomic loci for use in mutational analysis.
Mutant SOD1 causes dysfunction and structural damage of mitochondria in cultured neuronal cells [ 18 19 20 ] and at early disease stages in mutant SOD1 transgenic mice [ 21 22 ] . Human ALS also shows mitochondrial damage, dysfunction and loss [ 23 24 ] . The mechanism whereby mutant SOD1 causes mitochondrial damage has not been determined, but recent evidence shows that mutant SOD1 is imported into mitochondria [ 21 25 26 ] , and this mitochondrial localization may cause direct damage to mitochondria and induce cell death [ 27 ] . Consistent with this possibility, previous work suggested that mitochondrial vacuolation was developed from expansion of the intermembrane space [ 17 ] . However, the possibility that the vacuoles represent autophagic vacuolation has not been ruled out, because the source of the vacuolar membrane was not known.
[ 28] Initial screening of α-ALS and α-Dα2 sera showed no cross-reactivity in western blots when Drosophila and Calliphora brain homogenates were compared (data not shown).
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