Example sentences for: alanine

How can you use “alanine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For W89, an alanine substitution has been shown to prevent binding of [ 3H]granisetron; therefore a less severe mutation was constructed.

  • In L1, the residue at position 224 is a serine [ 35 ] , and the substrate-binding model for L1 predicts that this serine residue interacts with the carboxylate on substrate via a water molecule [ 37 ] . To test the proposed role of Ser224 in L1, serine was changed to an alanine (S224A), aspartic acid (S224D), and lysine (S224K), and these mutants were characterized using metal analyses, CD spectroscopy, steady-state kinetics, and pre-steady state kinetic studies.

  • This reduction was active-site dependent: adding back multicopy HNT2 with the nucleophilic histidine replaced by alanine or aspartate reduced dinucleoside polyphosphate levels less than two-fold.

  • These results showed that single alanine substitutions are insufficient to disrupt the LcrG-LcrV interaction.

  • Mutation of F48 to either alanine or leucine had no effect on the function of those LcrG variants, suggesting that the hydrophobic nature of F48 is important for LcrG function.


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