Example sentences for: affinity

How can you use “affinity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Both proteins were competent for binding a high affinity NFAT site when tested in electrophoretic mobility shift assays (Figure 4B).

  • It is known that during clonal selection in the thymus, immature CD4, CD8 double positive cells develop into single positive CD4 or CD8 cells according to the relative affinity of their TCR to class II or class I molecules respectively [ 5 6 ] . These immature T-cells are selected in the thymic epithelium on the basis of their TCR interaction with either class I or class II MHC molecules [ 7 8 ] , thus generating two mutually exclusive subpopulations that are characterized by the expression of either CD4 or CD8 glycoproteins [ 9 ] . Earlier studies in the murine system have demonstrated that PMA and cAMP can modulate the expression CD4 and CD8 on developing thymocytes [ 10 11 12 13 ] . In keeping with these findings, ex vivo experiments with human thymocytes previously reported by our group, revealed that while phorbol esters can coordinately regulate the transcription of α and β TCR during intrathymic T cell differentiation [ 14 ] , cAMP selectively affected the transcription of the α and δ-TCR [ 15 16 ] . Together the murine data and our own findings support the hypothesis that in humans, TCR expression and CD4, CD8 commitment and selection may be regulated by the same signal-transduction pathways.

  • The 3D affinity grid fields were created using the auxiliary program AutoGrid.

  • The affinity and electrostatic potential grid was calculated for each type of atom in the protease molecule.

  • These results demonstrated that CM and CM PEDFcontained heparin- and HS-like molecules, demonstrating that Y-79 cells produced GAGs with binding affinity for PEDF.

How many words do you know? Try our free vocabulary size test!


Search for example sentences

Loading Loading...