Example sentences for: affinity

How can you use “affinity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • On the basis of a simple two-state model, one might predict an increased affinity of the agonist for the mutant form, but in our studies binding of the agonist, unlike the antagonist, is not affected by the activating mutation, suggesting that a more complex model requiring two binding sites and perhaps multiple active conformations is needed to account for the observations.

  • The affinity of norepinephrine for the mutated receptor lacking two of the hydroxyl residues was approximately twice as high as the wild-type.

  • Two family members, acidic fibroblast growth factor (FGF-1) and FGF-2, have a strong affinity for heparin and have been studied for their effects on vascular cells, including endothelial cells and smooth muscle cells.

  • This inability to dimerize substantially decreases the enzymes affinity for DNA consequently impairing its polymerase and RNase H activities.

  • Olanzapine is a newer atypical antipsychotic agent with a pharmacological profile very similar to that of clozapine [ 11 ] . In human brain tissue, olanzapine displays very high affinity for the H1 histamine receptor, high affinity for 5-HT2A and 5-HT2C receptors [ 12 ] . In addition it also shows affinity for D2, muscarinic, and alpha1 receptors, with lower affinity for alpha2, 5-HT1D and 5-HT1A receptors (Table 1 [ 12 ] ).


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