Example sentences for: af-

How can you use “af-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In other cases, however, the balance of coactivator and corepressor recruitment is regulated by direct competition for the AF-2 surface, rather than ligand-dependent coregulator exchange.

  • Moreover, this interaction is dependent upon ERβ AF-2, including H12, and is competed by NR box peptides but not ID peptides.

  • AF-1 Activation function 1

  • Thus, ERβ interactions with N-CoR are dependent on the AF-2 surface (including H12) and, in this regard, resemble those of ERβ and GRIP1.

  • In the case of the RARγ2, degradation requires a constitutive phosphorylation of the AF-1 domain, heterodimerisation with RXR, and the presence of ligand indicating that the receptor has to be transcriptionally active to be degraded [ 42].


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