Words similar to af-

Example sentences for: af-

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Previously we characterized another RARα mutant in which the receptor protein was truncated after amino acid 403, thereby deleting the AF-2 domain [ 11 ] . This truncated receptor exhibited similar properties to the S77A mutant (growth inhibition and repression of RA responsive gene expression including EGFR).
AF-2 Activation function 2
Moreover, this interaction is dependent upon ERβ AF-2, including H12, and is competed by NR box peptides but not ID peptides.
Thus, ERβ interactions with N-CoR are dependent on the AF-2 surface (including H12) and, in this regard, resemble those of ERβ and GRIP1.
Together, our results indicate that ERβ has the potential to utilize its AF-2 surface to bind NR boxes within coactivators or an NR box-like sequence in the C-terminus of N-CoR.