Words similar to admixture
Example sentences for: admixture
How can you use “admixture” in a sentence? Here are some example sentences to help you improve your vocabulary:
This disorder is typically associated with homozygosity for the C282Y mutation of the HFE gene (exon 2, nt 845 G→A) on Ch6p [ 1 ] . C282Y lies within an ancestral haplotype which includes the human leukocyte antigen (HLA) haplotype A*03-B*07 [ 2 3 4 5 ] . The ancestral haplotype is the predominant hemochromatosis-associated haplotype in many northwestern European countries, including Ireland [ 6 ] , Brittany [ 2 ] , Denmark [ 7 8 ] , Sweden [ 9 ] , and Germany [ 10 11 ] . This is attributed to the origin of the C282Y mutation on an A*03-B*07 haplotype in northwestern Europe and its early dissemination by Vikings [ 3 12 ] . Modification of the ancestral chromosome by recombination and admixture as a result of geographic migration explains the occurrence of chromosomes bearing C282Y in association with different HLA haplotypes [ 2 4 8 13 14 15 16 ] . Thus some non-ancestral haplotypes also occur with significantly increased frequencies in hemochromatosis patients in various countries in Europe and in descendants of Europeans [ 5 16 ] .
In fact, distinct and dispersed subsets of proteins having the same substrate specificity may exist within a single protein family whose members possess an admixture of different substrate specificities.
Two-point linkage in the presence of locus heterogeneity was assessed by the admixture test of Ott, using HOMOG [ 36 ] . We used a heterogeneity LOD (HLOD) of > 1.3 to indicate nominal evidence for linkage for all linkage analyses [ 37 ] .
Considering that PBMCs represent an admixture of multiple cell types, the most plausible explanation is a simple lack of shift in subcellular populations.
One of the causes for conflicting results in candidate gene studies and in particular for spurious associations is believed to be population stratification or admixture [ 25 ] . Population stratification refers to the presence of subgroups, e.g. ethnic groups, in the sample and can potentially cause a spurious association between the locus and trait.
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