Example sentences for: adjuvant

How can you use “adjuvant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Nine patients with T1N0 disease and 5 patients with T2N0 disease and one patient each with T1N1 and T2N1 disease did not receive adjuvant radiotherapy.

  • Immunizations (1 mg of each peptide emulsified with incomplete Freund's adjuvant) were administered every 2 wk for 8 wk, then every 4 wk for 12 wk, and then once 8 wk later.

  • Recent work by Matthys et al . demonstrates that the protective effect of IFN-γ is dependent on the presence of the mycobacterial component of the adjuvant [ 36 ] . Only when mice are immunized with collagen in CFA is there an increase in disease severity in IFN-γ receptor-deficient mice.

  • Incomplete Freund's Adjuvant was used for all subsequent immunizations.

  • Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.

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