Words similar to adjuvant
Example sentences for: adjuvant
How can you use “adjuvant” in a sentence? Here are some example sentences to help you improve your vocabulary:
Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.
To generate antisera with sensitivity for detecting mactinin, purified recombinant chicken α-actinin peptide was modified by coupling with dinitrophenol [ 17 ] and injected into two New Zealand white rabbits along with complete Freund's adjuvant, as described previously [ 6 ] . Boosts were done with peptide and incomplete Freund's adjuvant.
In adjuvant arthritis, which may not be dependent on antibodies, disease is increased in the absence of IL-4 [ 27].
After 3 weeks, the animals were boosted with the antigen in incomplete Freund's adjuvant.
Chicken type II collagen was used for generation of arthritis as described elsewhere [ 26 ] . Male and female WT, heterozygous IL-10 +/-and IL-10 -/-mice were immunized once with 100 μg chicken type II collagen emulsified in complete Freund's adjuvant (CFA) (Difco, Detroit, MI, USA) by intradermal injection at the base of the tail.
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