Example sentences for: adjuvant

How can you use “adjuvant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To establish antigen-induced arthritis (AIA), rabbits were sensitized to ovalbumin by intradermal injections of 5 mg ovalbumin emulsified in Freund's complete adjuvant.

  • Once in the tissue, monocytes undergo the poorly understood process of transformation to macrophages with altered morphology and function [ 19 ] . In arthritis, synovial macrophages might cause joint destruction by differentiating to bone-resorbing osteoclasts [ 20 ] or by releasing cartilage-degrading enzymes and cytokines, such as interleukin-1 and tumor necrosis factor-α [ 8 ] . It has therefore been suggested that therapies for chronic arthritis should be aimed at depleting joint mononuclear cells or controlling the activation of synovial macrophages [ 21 ] . Indeed, elimination of macrophages by clodronate-laden liposomes in rat models of adjuvant [ 22 ] and antigen-induced arthritis [ 23 ] induces amelioration of the arthritis.

  • Conversely, if Hawaiians receive apparently similar adjuvant therapy (i.e.

  • The mechanism by which M6P/IGF2R allelic loss in head and neck tumors increases the effectiveness of adjuvant chemotherapy is presently unknown, but it is clearly of clinical importance.

  • Second, radiation-induced damage or abnormality may induce a "tissue damage signal" in the solid tumors through radiation-mediated apoptosis [ 38 ] . There is mounting evidence that apoptotic cell death is not immunologically benign, but can trigger immune responses [ 39 40 ] . For example, cells treated with ultraviolet radiation can provide potent adjuvant function in vivo [ 41 ] . Sub-lethal radiation could result in altered expression of pro or anti-inflammatory chemokines [ 42 43 44 ] or increased expression of T cell co-stimlulatory molecules (i.e.


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