Example sentences for: adhesion

How can you use “adhesion” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The tetraspanins are a family of cell-surface proteins with four transmembrane domains, two extracellular loops, and conserved cysteine residues at key positions in the second extracellular loop [ 1 ] . They facilitate a wide array of functions, including cell activation, differentiation, adhesion, morphological changes, and motility, which may all relate to the promiscuous associations of these molecules with integrins and other signaling proteins within the cell membrane and the cytoskeleton.

  • For example, in the related Rip1-Tag5 model, the vascular addressins GlyCAM-1 and MAdCAM-1 are expressed in pre-malignant islets, but down-regulated in solid tumors; their downregulation coincides with lack of infiltration in this model of spontaneous anti-tumor immunity [ 19 ] . It is possible that sub-lethal radiation is altering the expression of endothelial adhesion molecules allowing binding and extravasation of activated tumor-specific lymphocytes.

  • It has also been reported that inhibition of endothelial nitric oxide synthases (using the non-selective NOS inhibitor L-NAME), induces endothelial adhesion molecules (ICAM-1 and VCAM-1) in HUVEC [ 24, 25].

  • We have shown that α-actinin is abundant in the bone marrow stroma matrix, presumably at focal adhesion sites [ 5 ] . We have also reported that a 31 kDa amino-terminal α-actinin fragment, which we have named mactinin, is generated by the degradation of extracellular α-actinin by monocyte-secreted urokinase [ 6 ] . Furthermore, we have demonstrated that mactinin is present in inflammation caused by Pneumocystis carinii pneumonia, by examining bronchoalveolar lavage fluid from mice with infection [ 6 ] . It was not present in mice not challenged with P. carinii , suggesting that inflammaton is necessary for mactinin formation.

  • Expression of the adhesion molecule ICAM-1 was found to be approximately 1.6 times the level of control.


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