Words similar to adaptor
Example sentences for: adaptor
How can you use “adaptor” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus c-crk interacts constitutively with downstream effectors such as C3G via its SH3 domains, and interacts in a phosphotyrosine dependent fashion with tyrosine phosphorylated receptors using its SH2 domain [ 39 ] . To analyze downstream signals regulated by these adaptor proteins, investigators have developed methods that target them to distinct cellular membrane compartments by using heterologous targeting sequences.
We describe a novel chimeric molecule approach that allows the analysis of signaling events regulated by adaptor proteins that require tyrosine phosphorylation by upstream signals for which we used the Cas protein as a model.
Libraries were prepared according to the double adaptor method [ 39] with the following modifications: DNA was sheared using the Hydroshear (Gene Machines, San Carlos, CA) at speed code 2 for 25 cycles.
Typically (for data coming from an external data source) these consist of two Java classes: a dialog box and the adaptor itself.
The adaptor protein Cas has several domains that are important for its function, an SH3 domain, a central substrate domain with up to 15 tyrosines that can serve as tyrosine kinase substrates for upstream kinases such as Src and Abl [ 19 42 43 ] , and a C-terminal Src binding domain with PXXP motifs for binding to the SH3 domain of Src, and two tyrosines providing docking sites for the Src SH2 domain upon phosphorylation [ 6 ] . The substrate domain of Cas has two major types of tyrosine motifs that can be phosphorylated and bind downstream effectors, YQXP (4 copies) and YDXP motifs (9 copies), suggesting that at least two classes of downstream effectors, one capable of binding to YDXP motifs and the other capable of binding to YQXP motifs, are assembled by this adaptor protein.
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