Words similar to adaptor
Example sentences for: adaptor
How can you use “adaptor” in a sentence? Here are some example sentences to help you improve your vocabulary:
Prior to ligation at 16°C overnight, 2 μl from each adaptor ligation for each tester population were combined to serve as an unsubtracted control and were diluted into 1 mL sterile water following ligation.
Analysis of the specific signals emanating from the second class of adaptor proteins has been difficult due to their dependence on upstream kinases for tyrosine phosphorylation of the substrate domains for subsequent assembly of downstream effectors.
While these upstream kinases lead to tyrosine phosphorylation of the adaptor and activation of downstream effectors, they usually also activate other signaling pathways that can confound analysis of the specific role of the tyrosine phosphorylated adaptor protein.
The adaptor protein Cas has several domains that are important for its function, an SH3 domain, a central substrate domain with up to 15 tyrosines that can serve as tyrosine kinase substrates for upstream kinases such as Src and Abl [ 19 42 43 ] , and a C-terminal Src binding domain with PXXP motifs for binding to the SH3 domain of Src, and two tyrosines providing docking sites for the Src SH2 domain upon phosphorylation [ 6 ] . The substrate domain of Cas has two major types of tyrosine motifs that can be phosphorylated and bind downstream effectors, YQXP (4 copies) and YDXP motifs (9 copies), suggesting that at least two classes of downstream effectors, one capable of binding to YDXP motifs and the other capable of binding to YQXP motifs, are assembled by this adaptor protein.
Sequencing electrophoresis was carried out by the PSU Nucleic Acid Facility using the nested 1 or 2R adaptor primers.
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