Example sentences for: adaptors

How can you use “adaptors” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The second class of phosphotyrosine dependent adaptors exemplified by proteins such as Cas, Dok, IRS-1 and 2 or Slp-76, as cytosolic adaptors, or LAT, TRIM or SIT as membrane anchored adaptors, also require the activation of upstream signals by tyrosine kinases for their function.

  • We recognize a need for additional adaptors to read other variants of GFF (particularly that generated by Artemis), and GenBank and EMBL flat-file entries.

  • Signals are initiated by tyrosine phosphorylation of upstream effectors that recruit these adaptors to assemble larger protein complexes by bringing downstream effectors to the distinct cellular compartments for activation.

  • Tyrosine phosphorylation of the substrate domain leads to the recruitment of other downstream adaptors such as crk and nck, as well as other downstream effectors possessing SH2 domains, and signaling events attributed to this domain include activation of the JNK MAPK pathway and control of adhesion and migration of cells [ 6 10 16 38 44 ] . We constructed a chimera between a kinase that phosphorylates Cas in vivo and the substrate domain of Cas, in order to determine events regulated by this domain.

  • One microliter of sample was added to 24 μl PCR master mix prepared using the reagents supplied in the kit, and cycling conditions commenced as follows: 75°C for 5 min to extend the adaptors; 94°C for 25 sec; and 27 cycles at 94°C for 10 sec, 66°C for 30 sec, and 72°C for 1.5 min.


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