Words similar to acyl
Example sentences for: acyl
How can you use “acyl” in a sentence? Here are some example sentences to help you improve your vocabulary:
The modules each contain an acyl transferase (to load the extender unit onto the enzyme), as well as a ketosynthase and an ACP domain, together with exactly those reductive activities needed to generate the required pattern of modification of the chain at each step of elongation.
The DNA sequences responsible for such PKSs revealed sets of genes encoding proteins, including ketosynthases, ketoreductases, and acyl carrier proteins (ACPs) (the unit of the PKS on which the growing carbon chain is tethered; see Figure 1A), that would come together to form a multicomponent PKS resembling a typical bacterial fatty acid synthase.
Examples of such gene fusions are the multifunctional enzymes Aas (2-acylglycerophospho-ethanolamine acyl transferase and acyl-acyl carrier protein synthetase) and G1mU ( N -acetyl glucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyl transferase) [ 19, 20].
In the case of pNPP hydrolysis, others have reported both saturated and unsaturated fatty acyl coenzyme A esters stimulate PP5 activity, with concentrations required for half-maximal stimulation approximately 10-fold lower than those of their corresponding free fatty acids [ 21 ] . We therefore tested whether a saturated fatty acyl coenzyme A ester could also stimulate Ppt1p.
In the liver, intestine, adipose, and mammary gland, the cytoplasmic form synthesizes acetyl CoA for lipogenesis [ 46 ] . It is regulated by SREBP-1a, -1c- and -2, as well as SP1 and SP3 binding to GC-boxes; the promoter also contains an E-box [ 47 ] . It is down regulated with fasting, and induced with re-feeding; such dietary regulation does not exist in SREBP-1 knockout mice [ 48 ] . More generally, acyl CoA synthase is reported to be PPARα-activated [ 49 ] . The observed down regulation is consistent with less acetyl CoA available for the ACC reaction, as well as a plethora of other reactions.
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