Example sentences for: acyl

How can you use “acyl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This observation suggests that the chemical composition and properties of tissue membranes, specifically the acyl chains of the membrane phospholipids, directly influence the magnitude of the phase angle of an individual.

  • The finding of higher proportions of the high melting saturated fatty acids and lesser amounts of the PUFA with lower melting points in the red cell phospholipids of the SCD subjects relative to the controls prompted us to asses the overall impact of these differences on the relative fluidity of the acyl chains of the phospholipids from the red cells of the SCD patients and the controls by estimating the MMP of the phospholipids using the approach of Jensen and Patton [ 20 ] . The calculated MMP of the SCD subjects was significantly higher than for the controls, 29°C vs 24°C, p < 0.001.

  • In the liver, intestine, adipose, and mammary gland, the cytoplasmic form synthesizes acetyl CoA for lipogenesis [ 46 ] . It is regulated by SREBP-1a, -1c- and -2, as well as SP1 and SP3 binding to GC-boxes; the promoter also contains an E-box [ 47 ] . It is down regulated with fasting, and induced with re-feeding; such dietary regulation does not exist in SREBP-1 knockout mice [ 48 ] . More generally, acyl CoA synthase is reported to be PPARα-activated [ 49 ] . The observed down regulation is consistent with less acetyl CoA available for the ACC reaction, as well as a plethora of other reactions.

  • 4. This is also consistent with the suggestion, made in a recent report showing that cystic fibrosis isolates of P. aeruginosa had lipid A isoforms derivatized with aminoarabinose (or palmitate), that these structural modifications could enhance resistance to cationic antimicrobial peptides [ 61 ] . Although the acyl chains of lipid A might also provide alternative binding sites for protegrin, the orientation of lipid A on the HPA sensor chip ("butter-side down") probably removes them from consideration, at least under our study conditions.

  • The incorporation of 20:4n6 and 22:4n6 following feeding of the AA-rich FUNG diet, and the incorporation of 20:5n3, 22:5n3, and 22:6n3 following feeding of the EPA/DHA-rich FISH diet, into whole brain, hippocampal, and hepatic phospholipid (PL) pools (Table 1) was further evidence the diets were consumed, resulting in significant changes to PL acyl composition.


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