Example sentences for: acyl

How can you use “acyl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The modules each contain an acyl transferase (to load the extender unit onto the enzyme), as well as a ketosynthase and an ACP domain, together with exactly those reductive activities needed to generate the required pattern of modification of the chain at each step of elongation.

  • In these proteins, the GOLD domain co-occurs with lipid-, sterol- or fatty acid-binding domains such as PH [ 20, 21], Sec14p [ 22], FYVE [ 23], oxysterol binding- and acyl CoA-binding domains, suggesting that these proteins may interact with membranes.

  • Finally, the MP fractions were summed and 100 was subtracted from that sum to provide the estimate of the MMP of the acyl chains of the phospholipid preparation.

  • In the liver, intestine, adipose, and mammary gland, the cytoplasmic form synthesizes acetyl CoA for lipogenesis [ 46 ] . It is regulated by SREBP-1a, -1c- and -2, as well as SP1 and SP3 binding to GC-boxes; the promoter also contains an E-box [ 47 ] . It is down regulated with fasting, and induced with re-feeding; such dietary regulation does not exist in SREBP-1 knockout mice [ 48 ] . More generally, acyl CoA synthase is reported to be PPARα-activated [ 49 ] . The observed down regulation is consistent with less acetyl CoA available for the ACC reaction, as well as a plethora of other reactions.

  • Cpt1 transfers acyl residues from CoA to carnitine in the intermembrane space of the inner mitochondrial membrane, and has a regulatory role in controlling hepatic β-oxidation [ 50 ] . Cpt2 transfers carnitinoyl residues to CoA in the mitochondrial matrix for β-oxidation.


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