Example sentences for: acetyl-

How can you use “acetyl-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • IL-8, MCP-1 and RANTES gene expression are regulated by the redox responsive transcription factor NF-κB [ 18 20 23 25 26 27 28 29 30 31 32 33 41 42 43 44 ] . The NF-κB signaling pathways have been shown to be differentially affected by antioxidants and glucocorticoid steroids [ 45 ] . To determine whether RSV and TNFα induction of chemokine expression might be mediated by different NF-κB signaling pathways we pretreated A549 cells with the glutathione precursor N-acetyl-L-cysteine (NAC) or the synthetic glucocorticoid dexamethasone (DEX).

  • 2-Amino-3-carboxymuconate semialdehyde can be considered to be a branchpoint metabolite that either enters committed catabolism to acetyl-CoA or that enters biosynthesis to NAD +/NADP +. In the central nervous system, a number of kynurenine-pathway metabolites are neuroactive and appear to be involved in inflammatory neurological diseases [ 32].

  • This uses the building units in the form of activated derivatives, called coenzyme A (CoA) esters, so we speak of acetyl-CoA and malonyl-CoA, for example.

  • Visual examination of the structure of this insert domain revealed a topology with elements of both a sandwich and a barrel, and two "waist"-like structures that are characteristic of the sandwich-barrel hybrid motif (SBHM) fold [ 75 76 ] (see also the SCOP database [ 65 ] ). The SBHM fold is present in biotin/lipoate carrier domains and their homologs found in a variety of enzymes and transporters [ 76 ] . A DALI search with this insert domain from the β subunit of Thermus DDRP showed similarity to the SBHMs from various biotin/lipoate-binding enzymes, such as acetyl-CoA carboxylase (1bdo) or dihydrolipoamide acetyltransferase (1iyu) with Z scores of ~6 and RMSD ~2.

  • Most aromatic polyketides start with acetyl-CoA.

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