Example sentences for: acetyl

How can you use “acetyl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Many genes that are known to amplify in response to selection, primarily during anticancer drug treatments, were found to be present in multiple copies in mammalian genomes as well, in particular, aminoacyl-tRNA synthetases, glutamine synthetase and other anabolic enzymes, adenosine deaminase, ornithine decarboxylase, AMP deaminase, and N -acetyl glucosaminyltransferase [ 34, 46].

  • These polymers belong to several classes: (1) sulfate esters of polysaccharides (dextrin and dextran sulfates [ 1 2 3 4 5 6 7 8 9 10 11 ] ; cellulose sulfate [ 12 13 14 15 ] ; sulfate esters of galactose + 3,6-anhydrogalactose copolymers {carrageenan; [ 1 16 17 18 19 ] }); (2) polymers containing sulfonated benzene or naphthalene rings {poly(styrene-4-sulfonate) [ 20 21 ] } and naphthalene sulfonate polymers {PRO2000 [ 22 23 24 ] }; and (3) polycarboxylates (acrylic acid polymers {Carbomer 974P; BufferGel [ 25 26 27 28 29 ] }); and acetyl phthaloyl cellulose {cellulose acetate phthalate (CAP) [ 30 31 32 33 34 35 36 37 ] }.

  • aa, amino acid; Ab, antibody; bp, base pair; CaPO 4 , calcium phosphate; C/EBPβ, CCAAT-enhancer binding protein-beta; CAT, chloramphenicol acetyl transferase; DMEM, Dulbecco's Modified Eagle Medium; GST, glutathione-S-transferase; MAPK, mitogen activated protein kinase; PBS, phosphate buffered saline; PMSF, phenylmethylsulfonyl fluoride; SRE, serum response element; SRF, serum response factor; TCF, ternary complex factor.

  • In the liver, intestine, adipose, and mammary gland, the cytoplasmic form synthesizes acetyl CoA for lipogenesis [ 46 ] . It is regulated by SREBP-1a, -1c- and -2, as well as SP1 and SP3 binding to GC-boxes; the promoter also contains an E-box [ 47 ] . It is down regulated with fasting, and induced with re-feeding; such dietary regulation does not exist in SREBP-1 knockout mice [ 48 ] . More generally, acyl CoA synthase is reported to be PPARα-activated [ 49 ] . The observed down regulation is consistent with less acetyl CoA available for the ACC reaction, as well as a plethora of other reactions.

  • Although ACC was not regulated at the transcriptional level, cytoplasmic citrate (generated from the Acly reaction) is an allosteric activator of ACC, so less cytoplasmic citrate would lead to less activation of ACC [ 45 ] . Transcript levels of hepatic acetyl CoA synthetase 1 AMP forming (acetate:CoA ligase AMP forming; Acas1) were consistently down regulated by LC-PUFA (-2.


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