Words similar to acceptor
Example sentences for: acceptor
How can you use “acceptor” in a sentence? Here are some example sentences to help you improve your vocabulary:
The plasmid pBigT consists of the adenovirus splice acceptor sequence followed by a loxP site, neo expression cassette, strong transcriptional stop sequence (triple SV40 polyadenylation sequence), another loxP site in the same orientation as the first, a multiple cloning site (MCS), and the bovine growth hormone polyadenylation sequence.
Additionally, both the mouse and human Abcg8 genes have alternatively spliced mRNA, involving a CAG repeat at exon 2 and exon 8 splice acceptor sites respectively [ 12 14 ] . However, despite the presence of such a repeat at the rat exon 2 splice acceptor site for Abcg8 (Table 2), none of the rat mRNAs showed any heterogeneity of splice-site selection at this site.
For example, Lawrence and Ochman [ 4 ] hypothesized that the recently transferred genes were adapted to the genomic context of other distant species; however, our results would suggest either that the donor genomes are always more A+T rich than the acceptor genomes or that there is a bias toward the internalization of A+T-rich exogenous DNA in the genome.
The details of the genomic organization of the gene are shown in Table 1and Figure 2. All but two of the resulting intron-exon boundaries concur with the typical splice donor and acceptor motif-GT/AG.
Rab proteins comprise a large family of Ras-related GTPases that function in the anterograde and retrograde trafficking of proteins in mammalian cells [ 1 2 3 ] . Different Rab proteins reside in specific subcellular membranes or organelles, where they mediate vesicular transport between discrete donor and acceptor compartments in the endocytic or exocytic pathways [ 4 5 ] . Detailed studies of a few Rab proteins ( e.g .; Rab1, Rab5 and Rab9) have led to a general model wherein Rab proteins are presumed to cycle on and off donor and acceptor membranes in connection with changes in their guanine nucleotide state [ 6 7 8 ] . In the active GTP-bound state, Rab proteins associate with budding transport vesicles [ 9 10 11 ] and appear to participate in the assembly of membrane docking complexes [ 12 13 14 ] . Following vesicle fusion with the acceptor compartment and GTP hydrolysis, the inactive GDP-bound Rab is extracted from the membrane by a carrier protein termed guanine nucleotide dissociation inhibitor (GDI) [ 15 16 17 ] . The GTPase can then re-enter the transport cycle through nucleotide exchange promoted by a specific exchange factor at the donor vesicle membrane [ 18 19 20 ] . In addition to changes in guanine nucleotide state, the posttranslational prenylation of Rab proteins plays an important role in the cycling mechanism.
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