Example sentences for: acceptor

How can you use “acceptor” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The region between -50 and -10 upstream from the acceptor site was examined for a branch point signal and the corresponding branch point score was calculated (Table 1).

  • Rab proteins comprise a large family of Ras-related GTPases that function in the anterograde and retrograde trafficking of proteins in mammalian cells [ 1 2 3 ] . Different Rab proteins reside in specific subcellular membranes or organelles, where they mediate vesicular transport between discrete donor and acceptor compartments in the endocytic or exocytic pathways [ 4 5 ] . Detailed studies of a few Rab proteins ( e.g .; Rab1, Rab5 and Rab9) have led to a general model wherein Rab proteins are presumed to cycle on and off donor and acceptor membranes in connection with changes in their guanine nucleotide state [ 6 7 8 ] . In the active GTP-bound state, Rab proteins associate with budding transport vesicles [ 9 10 11 ] and appear to participate in the assembly of membrane docking complexes [ 12 13 14 ] . Following vesicle fusion with the acceptor compartment and GTP hydrolysis, the inactive GDP-bound Rab is extracted from the membrane by a carrier protein termed guanine nucleotide dissociation inhibitor (GDI) [ 15 16 17 ] . The GTPase can then re-enter the transport cycle through nucleotide exchange promoted by a specific exchange factor at the donor vesicle membrane [ 18 19 20 ] . In addition to changes in guanine nucleotide state, the posttranslational prenylation of Rab proteins plays an important role in the cycling mechanism.

  • Competition between the alternative splice sites depends on the relative quality of the different constitutive splice signals and we found that the acceptor strength probably plays a major role in this regulation.

  • Some of these variants have been independently observed by other groups: NF1ins4a-2 [ 14 15 16 ] , NF1ΔE4b [ 14 15 16 ] , NF1ΔE7 [ 15 19 ] , NF1ΔE29/E30 [ 11 ] , NF1ΔE30 [ 11 ] , NF1ΔE33 [ 16 ] , NF1ΔE34 [ 16 ] , NF1ΔE37 [ 15 16 ] , NF1ΔE43 [ 16 ] , NF1-Δ7605-7675 [ 16 ] and NF1ΔE45 [ 16 ] . Some of these transcripts increased with time or cold shock [ 14 16 ] . It has been shown that ~30 % of NF1 germline mutations result in splicing errors [ 13 20 ] . The vast majority of them are due to alterations outside the canonical AG/GT acceptor and donor splice sites.

  • through increased specificity of phosphate uptake, [ 2 ] ), arsenite oxidation through the activity of arsenite oxidase [ 3 4 ] , or peroxidation reactions with membrane lipids [ 5 6 ] . Other microorganisms utilize arsenic in metabolism, either as a terminal electron acceptor in dissimilatory arsenate respiration [ 7 8 9 10 ] or as an electron donor in chemoautotrophic arsenite oxidation [ 11 12 ] . However, the most well-characterized microbial arsenic detoxification pathway involves the ars operon [ 2 13 ] .


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