Example sentences for: abl

How can you use “abl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mutations in the ABL kinase domain are found in 50%–90% of patients with secondary resistance to the drug (reviewed in [8]).

  • Imatinib (Gleevec), a 2-phenylaminopyrimidine, is a competitive inhibitor of ATP binding to the ABL kinase, thereby inhibiting the constitutively activated BCR-ABL tyrosine kinase.

  • This fact is reflected in the analysis of literature profiles, as groups of genes could be found to be associated with brain tissues (Figure 7f, for example, HPCA (hippocalcin), SYP (synaptophysin), GRIK1 (glutamate receptor, ionotropic, kainate 1), APLP (amyloid beta A4 precursor-like protein)), immune cells (Figure 7b, for example, CD40, IL15RA (IL-15 receptor, alpha chain), LILB4 (leukocyte immunoglobulin-like receptor 4)) or tumor cells (Figure 7a, for example, MYBL1 (v- myb avian myeloblastosis viral oncogene), ABL2 (v- abl Abelson murine leukemia viral oncogene homolog 2)).

  • There has been no report to link cellular ABL kinase mutation to any cancer patients except BCR-ABL in CML, although the detailed c-Abl function has not been extensively studied in lung cancer patients.

  • ARG shares significant homology with c-Abl throughout the amino acid sequences.


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