Words similar to aberrantly
Example sentences for: aberrantly
How can you use “aberrantly” in a sentence? Here are some example sentences to help you improve your vocabulary:
It has been proposed that loss of hERα expression in breast tumors is the result of aberrant RNA processing [ 40 41 42 43 ] . These aberrantly spliced mRNAs, if translated, could lead to truncated receptors with hormone binding but not DNA binding function [ 44 ] . Further, there is evidence for the role of RNA processing in oncogenesis [ 45 46 ] . Many studies, including those on human hnRNP A2/B1 and the CD44 gene, suggest that high fidelity pre-mRNA splicing is critical to normal cellular function and may play a key role in oncogenesis and breast cancer progression [ 47 48 ] . The strong association between nmt55/p54 nrband hERα expression indicates that nmt55/p54 nrbmay be an important marker for breast cancer progression.
In order to determine if Wnt signaling was aberrantly active in the cerebellar neuroblasts thought to give rise to some medulloblastomas, β-catenin immunostains were performed on newborn Mut-1 and Mut-2 animals.
In surveying the growing number of studies and claims of new cells that can acquire some type of heart cell phenotype in vitro or in vivo (for a review see [6]), it will become increasingly important to create a set of rigorous criteria that would distinguish between the following: authentic progenitor cells that are already committed to the cardiac lineage; pluripotent stem cells that can infrequently adopt the cardiac phenotype; phenotypic drift of other muscle progenitors with an increased propensity to enter cardiac lineages; and a variety of other cell types that can aberrantly express cardiac markers ectopically or by fusion with neighboring cardiac muscle cells.
The progression of breast cancer may be associated with changes in RNA processing and the production of aberrantly spliced mRNAs, which may result in non-functional gene products or the loss of specific gene expression.
The cerebellar phenotype in these mice was not reported, and it is not clear if the aberrantly proliferating neuroepithelial precursors in their mice represent a pre-neoplastic population.
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