Example sentences for: aberrantly

How can you use “aberrantly” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In order to determine if Wnt signaling was aberrantly active in the cerebellar neuroblasts thought to give rise to some medulloblastomas, β-catenin immunostains were performed on newborn Mut-1 and Mut-2 animals.

  • The progression of breast cancer may be associated with changes in RNA processing and the production of aberrantly spliced mRNAs, which may result in non-functional gene products or the loss of specific gene expression.

  • The mitogenic role played by Wnts in normal CNS development also supports the concept that the pathway could promote growth in the brain [ 21 22 ] . In order to test this hypothesis we created transgenic mice in which the Wnt pathway was aberrantly activated in the CNS.

  • Moreover, several recent studies have reported direct mapping of sites phosphorylated by Cdc5/Polo in vitro [ 22 29 32 ] , but in two of these cases the authors relied exclusively on phosphoshift analysis of mutant proteins to confirm that the same sites are phosphorylated in vivo . Given the significant possibility that multiply mutated proteins are not properly phosphorylated in vivo for indirect reasons, or migrate aberrantly upon SDS-PAGE, it may be prudent to perform direct mapping experiments to confirm unambiguously the physiological significance of sites phosphorylated by Cdc5/Polo in vitro .

  • If chromosomes segregated aberrantly during the MI reductional division, and then segregated appropriately during the equational division of MII, one would expect sister spores to receive identical complements of chromosomes.


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