Words similar to aberrantly
Example sentences for: aberrantly
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1%) were guanosine at this position in the splice sequence making it likely that exon 68 will be aberrantly spliced [ 23 ] . When these two fragments were run on the DHPLC system at the lower second pass temperatures indicated in Additional file A: Primer sequences and DHPLC temperatures Excel spreadsheet, the alterations were detected (Figure 2cand 2b).
Moreover, several recent studies have reported direct mapping of sites phosphorylated by Cdc5/Polo in vitro [ 22 29 32 ] , but in two of these cases the authors relied exclusively on phosphoshift analysis of mutant proteins to confirm that the same sites are phosphorylated in vivo . Given the significant possibility that multiply mutated proteins are not properly phosphorylated in vivo for indirect reasons, or migrate aberrantly upon SDS-PAGE, it may be prudent to perform direct mapping experiments to confirm unambiguously the physiological significance of sites phosphorylated by Cdc5/Polo in vitro .
In order to determine if Wnt signaling was aberrantly active in the cerebellar neuroblasts thought to give rise to some medulloblastomas, β-catenin immunostains were performed on newborn Mut-1 and Mut-2 animals.
The progression of breast cancer may be associated with changes in RNA processing and the production of aberrantly spliced mRNAs, which may result in non-functional gene products or the loss of specific gene expression.
The mitogenic role played by Wnts in normal CNS development also supports the concept that the pathway could promote growth in the brain [ 21 22 ] . In order to test this hypothesis we created transgenic mice in which the Wnt pathway was aberrantly activated in the CNS.
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