Example sentences for: aberrantly

How can you use “aberrantly” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Any drop in translation efficiency might alter the counting mechanism and result in aberrantly sized mounds.

  • In surveying the growing number of studies and claims of new cells that can acquire some type of heart cell phenotype in vitro or in vivo (for a review see [6]), it will become increasingly important to create a set of rigorous criteria that would distinguish between the following: authentic progenitor cells that are already committed to the cardiac lineage; pluripotent stem cells that can infrequently adopt the cardiac phenotype; phenotypic drift of other muscle progenitors with an increased propensity to enter cardiac lineages; and a variety of other cell types that can aberrantly express cardiac markers ectopically or by fusion with neighboring cardiac muscle cells.

  • Most of the peptides identified so far are either normal self proteins aberrantly expressed in cancer but not in most other adult normal tissues or tissue-specific antigens also expressed in certain types of cancer.

  • It has been proposed that loss of hERα expression in breast tumors is the result of aberrant RNA processing [ 40 41 42 43 ] . These aberrantly spliced mRNAs, if translated, could lead to truncated receptors with hormone binding but not DNA binding function [ 44 ] . Further, there is evidence for the role of RNA processing in oncogenesis [ 45 46 ] . Many studies, including those on human hnRNP A2/B1 and the CD44 gene, suggest that high fidelity pre-mRNA splicing is critical to normal cellular function and may play a key role in oncogenesis and breast cancer progression [ 47 48 ] . The strong association between nmt55/p54 nrband hERα expression indicates that nmt55/p54 nrbmay be an important marker for breast cancer progression.

  • Moreover, several recent studies have reported direct mapping of sites phosphorylated by Cdc5/Polo in vitro [ 22 29 32 ] , but in two of these cases the authors relied exclusively on phosphoshift analysis of mutant proteins to confirm that the same sites are phosphorylated in vivo . Given the significant possibility that multiply mutated proteins are not properly phosphorylated in vivo for indirect reasons, or migrate aberrantly upon SDS-PAGE, it may be prudent to perform direct mapping experiments to confirm unambiguously the physiological significance of sites phosphorylated by Cdc5/Polo in vitro .


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast