Words similar to aberrantly
Example sentences for: aberrantly
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In surveying the growing number of studies and claims of new cells that can acquire some type of heart cell phenotype in vitro or in vivo (for a review see [6]), it will become increasingly important to create a set of rigorous criteria that would distinguish between the following: authentic progenitor cells that are already committed to the cardiac lineage; pluripotent stem cells that can infrequently adopt the cardiac phenotype; phenotypic drift of other muscle progenitors with an increased propensity to enter cardiac lineages; and a variety of other cell types that can aberrantly express cardiac markers ectopically or by fusion with neighboring cardiac muscle cells.
1%) were guanosine at this position in the splice sequence making it likely that exon 68 will be aberrantly spliced [ 23 ] . When these two fragments were run on the DHPLC system at the lower second pass temperatures indicated in Additional file A: Primer sequences and DHPLC temperatures Excel spreadsheet, the alterations were detected (Figure 2cand 2b).
Moreover, several recent studies have reported direct mapping of sites phosphorylated by Cdc5/Polo in vitro [ 22 29 32 ] , but in two of these cases the authors relied exclusively on phosphoshift analysis of mutant proteins to confirm that the same sites are phosphorylated in vivo . Given the significant possibility that multiply mutated proteins are not properly phosphorylated in vivo for indirect reasons, or migrate aberrantly upon SDS-PAGE, it may be prudent to perform direct mapping experiments to confirm unambiguously the physiological significance of sites phosphorylated by Cdc5/Polo in vitro .
The progression of breast cancer may be associated with changes in RNA processing and the production of aberrantly spliced mRNAs, which may result in non-functional gene products or the loss of specific gene expression.
The cerebellar phenotype in these mice was not reported, and it is not clear if the aberrantly proliferating neuroepithelial precursors in their mice represent a pre-neoplastic population.
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