Words similar to aberrant
Example sentences for: aberrant
How can you use “aberrant” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, no tumors, pre-neoplastic changes or other CNS morphologic alterations were detected, suggesting that postnatal aberrant Wnt activation is not sufficient to induce CNS tumorigenesis in mice.
LNCaP cells contain high levels of functional AR with mutated ligand binding domain and exhibit aberrant cellular responses to androgen [ 5 37 38 ] . The mutated AR when interact with the ARE of the RAR-α gene, may trans-activate the gene in an abnormal fashion resulting in increases in its mRNA.
It has been proposed that loss of hERα expression in breast tumors is the result of aberrant RNA processing [ 40 41 42 43 ] . These aberrantly spliced mRNAs, if translated, could lead to truncated receptors with hormone binding but not DNA binding function [ 44 ] . Further, there is evidence for the role of RNA processing in oncogenesis [ 45 46 ] . Many studies, including those on human hnRNP A2/B1 and the CD44 gene, suggest that high fidelity pre-mRNA splicing is critical to normal cellular function and may play a key role in oncogenesis and breast cancer progression [ 47 48 ] . The strong association between nmt55/p54 nrband hERα expression indicates that nmt55/p54 nrbmay be an important marker for breast cancer progression.
Outliers Instances that are aberrant or do not fit with other instances; instances that, compared to other members of a population, are at the extremes on relevant dimensions.
It is believed that the pathogenic mechanism relates to aberrant thymidine metabolism giving rise to impaired mtDNA replication and/or mtDNA maintenance [ 22].
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