Example sentences for: aberrant

How can you use “aberrant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • An additional mutant transcript resulted from an aberrant splicing event from exon 7 to exon 8 such that 35 nucleotides (nt) of the 3' end of exon 7 were deleted (6,7Δ35,8 and 4,5,6,7Δ35,8).

  • An aberrant interaction between lymphocytes and different epithelial tissues has been proposed as a mechanism for the damage seen in different organs in 1° SS [ 36 ] . Since it has been suggested that the target tissue involved in the autoimmune histopathologic lesions of 1°SS might be the epithelium [ 37 ] , it is interesting that the findings in our study point to the association of liver disease with pulmonary and renal abnormalities, all which are characterized by epithelial damage [ 38 39 ] . Epithelial cells have been proposed to be active participants rather than passive targets in the chronic immune response in 1°SS but further studies are needed to establish the role of liver epithelial cells in the pathogenesis of hepatic damage in this disease, including the analysis of HLA expression and cytokine secretion pattern in these cells.

  • Compounds that inhibit SAM association could be effective in preventing activation of the aberrant SAM/tyrosine kinase fusions and consequent cell transformation.

  • Upregulation of CCR5 and CXCR3 on T cells and accumulation of these cells in the lung periphery suggest that aberrant, unremitting pulmonary recruitment of these activated T cells is unique to people with smoking-related lung disease, despite cessation of exposure to the inciting agent, tobacco smoke.

  • The latter might result from aberrant splicing or PCR artefacts.


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