Example sentences for: aberrant

How can you use “aberrant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The DQA1*0501 allele is strongly associated with early-onset pauciarticular JRA in Northern European populations [ 23 24 ] and with increased risk for juvenile dermatomyositis [ 25 ] and Sjögren's syndrome with high autoantibody production [ 26 27 ] . In our proposed model, aberrant class II MHC regulation could result from altered DEK binding and/or interaction with NF-Y, and aberrant class II expression may alter or enhance reactivity against DEK-derived or other self peptides.

  • Progression of granulation tissue to neodermis requires a decrease in cellularity through apoptosis of endothelial cells, fibroblasts and myofibroblasts [ 28 29 ] . Keloid fibroblasts demonstrate aberrant apoptotic behavior [ 30 31 ] although studies have given variable results [ 5 9 11 30 31 32 33 34 35 ] . Our initial data for serum-starvation-induced apoptosis in monolayer cultures of dermal fibroblasts demonstrated delayed apoptosis of keloid fibroblasts and a negative correlation with α-SMA expression [ 36 ] . Similar correlations were observed in rat lung fibroblasts, where TGFβ1 increased α-SMA content while acting as an antiapoptotic agent [ 37 38 ] . It should be noted however, that many of the myofibroblasts were still able to undergo apoptosis consistent with in vivo data on palatal wound healing [ 39 ] . Thus, TGFβ1 can promote both α-SMA expression in the initial stages of wound healing and apoptosis in later stages of wound healing.

  • Of course these principles do not account for all the streets in a particular development and do not necessarily apply in all developments, but I cannot be responsible for a developer's ignorance of my findings or for his aberrant conduct in disregarding them.

  • Various attempts to modify aberrant immune responses to specific allergens, such as those to cat dander, have been made.

  • [ 9 ] , but employed far greater doses of aspirin (45 and 90 mg/kg/day) and reported no dose-response relationship and a maximal suppression of 55% [ 7 ] . Furthermore, in the rat model of azoxymethane-induced colon carcinogenesis, aspirin has also only been found to inhibit aberrant crypt foci and tumour development by no more than 65% [ 4 39 ] . Coincidentally, epidemiological data also report reductions in the 40-50% range [ 13 14 15 32 ] . However, whether this can be used as an argument to support the notion that aspirin is only able to suppress tumour formation by 50% is difficult to extrapolate because two different end points are being examined (i.e.


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