Words similar to aberrant
Example sentences for: aberrant
How can you use “aberrant” in a sentence? Here are some example sentences to help you improve your vocabulary:
I told her to her face, [an aberrant piece of straight-talking, this] Don't you turn round to me and tell me I turned round and accused you of being two-faced.
It has been speculated that these modified forms of autoantigens may have enhanced immunogenicity through exposure of immunocryptic epitopes that are not generated during antigen processing [ 21 23 37 43 ] . These epitopes could trigger autoimmune responses if presented to the immune system under proinflammatory conditions [ 44 ] , and they may be recognized as surface structures on cytoplasmic organelles that are released to the immune system in aberrant disease states.
The phenotype induced by ADP-ribosylation of Rho in T lymphocytes appeared different than that induced in fibroblast models, where microinjection of C3 results in fibroblast retraction of pseudopodia, with the cell body rounding up eventually to become non-adherent [ 17 ] . Video time-lapse microscopy demonstrated the elongation of aberrant pseudopods in HPB-ALL cells plated on the β1 substrate VCAM-1, rather than an altered retraction of already formed pseudopods.
Aberrant promoter methylation changes that occur in cancer are associated with transcriptional repression and loss of function of the gene by interrupting the binding of proteins involved in transcription activator complex [ 12 ] . Our gene expression analysis by RT-PCR demonstrated that all tumors that showed methylation of MGMT and MLH1 also showed down-regulated expression, while RASSF1A and RARB genes showed down-regulation of mRNA levels in most of the methylated tumors.
Consistent with this, clones of pBS58 carrying D96A and D166K/F268V showed aberrant Z-ring formation at 30°C, and E250K/D253K showed fragility and cell lysis.