Example sentences for: aberrant

How can you use “aberrant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These findings are in contrast to allelotyping studies, which show higher rates of abnormalities in patients with significant tobacco/alcohol exposure [ 4 ] . Since tobacco is known to cause single strand breaks, it may be aberrant repair of these changes that is detected by LOH, which are below the threshold of detection by CGH.

  • Thus in our transgenic animals, aberrant Wnt activation appears to be limited to mature, postmitotic neurons.

  • Another approach to flow cytometric detection of tumor cells has been the identification of phenotypically aberrant populations that express different amounts of cell surface proteins than normal T-cell populations.

  • Promoter methylation has been well recognized as an important epigenetic change in the development of cancer [ 1 ] . Normally, CpG islands in the promoter regions of a number of genes are present in an unmethylated state [ 2 ] . Aberrant methylation of CpG islands in promoters is characteristic of several genes in cancer leading to loss of gene expression.

  • Acquired resistance to kinase-targeted anticancer therapy has been most extensively studied with imatinib, an inhibitor of the aberrant BCR-ABL kinase, in chronic myelogenous leukemia (CML).


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