Example sentences for: aberrant

How can you use “aberrant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Infection of cultured podocytes with replication incompetent HIV-1 demonstrated that HIV-1 gene expression leads to the proliferation and dedifferentiation of the infected podocytes [ 6 7 8 ] , recapitulating the phenotypes observed in HIVAN specimens [ 9 10 ] . Similarly, renal expression of replication incompetent HIV-1 proviral transgenes in mice and rats produces a proliferative renal lesion that is indistiguisable both histopathologically and clinically from human HIVAN [ 11 12 13 14 ] . These observations raise the possibility that HIV-1 gene products may interact with mitogenic pathways in infected renal epithelium to cause aberrant cell-cycle engagement.

  • Acquired resistance to kinase-targeted anticancer therapy has been most extensively studied with imatinib, an inhibitor of the aberrant BCR-ABL kinase, in chronic myelogenous leukemia (CML).

  • The GFP-BLM fusion protein accumulates in the same nuclear structures as determined previously [ 20] and does not appear to cause aberrant structures at the levels expressed here.

  • In conclusion, we found that the absence of CD26 and other aberrant surface expression of T cell-associated markers allowed identification of a discrete, quantifiable population in nearly all MF/SS patients with PB tumor cells.

  • Another mutant transcript included an aberrant mini-exon of 37 nt of ETn derived-sequences inserted between the 3' deleted exon 7 to exon 8 splice (6,7Δ35,+37ETn,8 and 4,5,6,7Δ35,+37ETn,8).

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