Example sentences for: pathophysiological

How can you use “pathophysiological” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Several researchers have also evaluated ibuprofen, and beneficial effects on pathophysiological changes have been observed [ 3 ] . The first major study of ibuprofen in endotoxic shock was performed by Jacobs et al.

  • In small wounds, the pathophysiological process caused by the cell-matrix interaction-related defects may be too small to affect reepithelialization significantly with the result that restoration of epidermal covering progresses as normally as in the wild-type mice.

  • Although at the present time it is difficult to comment on the pathophysiological significance of increased MMP-9 release, it is perhaps noteworthy that increased MMP-9 expression has been correlated with increased apoptosis [ 52 ] and increased microvascular permeability [ 53 ] , events possibly involved in the opening of the blood-brain barrier [ 54 ] and potential injury to the brain [ 50 ] .

  • It has been indicated that the pathway of cyclooxygenase products, such as TxB 2 and PGE 2 , increases in many endotoxic shock models and plays an important role in a number of pathophysiological events [ 21 27 ] .

  • Members of the Ets family of transcription factors share a unique DNA binding domain, the Ets domain, and have been shown to activate a large number of genes [ 42 43 ] and to be involved in a number of physiological and pathophysiological processes [ 44 ] . There has been accumulating evidence that Ets proteins play an important part for the invasive program of cells, particularly by stimulating the expression of protease genes [ 45 46 ] . Ets1 and Ets2 are overexpressed in a variety of tumors, including breast carcinomas ( [ 44 ] and references therein).


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