Example sentences for: pathologies

How can you use “pathologies” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • TNF-α is a cytokine that can mediate myelin and oligodendrocyte damage in vitro [ 10 ] and thought to play a key role in central nervous system pathologies [ 3 ] . In vitro E. coli LPS can trigger rat neonatal microglia to rapidly activate TNF-α gene expression and subsequent protein release [ 46 ] in a concentration- and time-dependent manner.

  • Gene therapy represents a novel approach for delivery of therapeutic agents to joints in order to treat the pathologies associated with RA and osteoarthritis, as well as other disorders of the joints.

  • "Let's face it, the pathologies are severe in these areas," Jackson said.

  • Previously, we and others have shown that local ex vivo and in vivo gene transfer of v-IL-10, IL-1Ra, IFN-γ, soluble IL-1 receptor, and soluble TNF receptor are able to block certain intra-articular pathologies in rabbit, rat, and murine models of arthritis.

  • Since TGF-β1 has anti-inflammatory properties as well as being able to stimulate new matrix synthesis by chondrocytes, it represents a possible therapeutic agent with which to treat pathologies associated with rheumatoid arthritis and osteoarthritis by local gene delivery.


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