Example sentences for: ionophore

How can you use “ionophore” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Calcium is an established stimulator of LH secretion that is thought to act at sites downstream of phospholipase C [ 39 40 ] . Therefore, adeno-RGS3 infected pituitary cells were treated with a calcium ionophore (A23187).

  • Arguing for the specificity of this effect is the stimulation of LH secretion by a calcium ionophore and the failure of LH stores and GnRH-receptor binding to be affected by RGS3.

  • Upon treatment with the calcium ionophore ionomycin, GFP-NFAT translocates rapidly to the nucleus.

  • Phosphorylation of cPLA 2 on Ser 505has been hypothesized to play a role in Ca 2+-mediated translocation since Ser 505phosphorylation is required for cPLA 2 -mediated AA release in response to low-dose, but not high-dose, ionophore [ 22 ] . Translocation of cPLA 2 S505A in CHO cells has been reported in response to ionophore stimulation [ 25 ] , but the effect of Ser 505phosphorylation on the kinetics of translocation, targeting, and in response to a physiological agonist was not investigated.

  • For example, cPLA 2 constructs with a S505A mutation have long been recognized as unable to support AA release in response to physiological agonists or low-dose ionophore when transfected in cells.


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