Words similar to ionizing
Example sentences for: ionizing
How can you use “ionizing” in a sentence? Here are some example sentences to help you improve your vocabulary:
The product of the Ataxia Telangiectasia gene, the ATM protein kinase [ 9], directly phosphorylates serine 15 of the p53 protein in response to Ionizing Radiation [ 10, 11].
However, when cells were exposed to Ionizing Radiation, GSK3β kinase activity was inhibited rather than enhanced, implying decreased GSK3β-dependent phosphorylation of p53 after DNA damage.
When asynchronously growing cells were exposed to 5Gy or 10Gy of Ionizing Radiation to cause DNA damage, the levels of GSK3β activity were reduced.
In 1990, the US Environmental Protection Agency (EPA) identified nine developmental neurobehavioral teratogens for both humans and animals (lead, PCBs, methyl mercury, cocaine, alcohol, phenytoin, heroin, methadone, and ionizing radiation) and developed rules for DNT testing in laboratory animals [49,50].
In response to DNA damage induced by ionizing radiation or chemical agents such as cisplatin, ATM kinase is activated and phosphorylates a number of downstream regulatory proteins important for cell cycle arrest, growth control, apoptosis and DNA repair [ 25 26 27 28 ] . AT patients are known to be predisposed to a variety of cancers, and the fibroblasts of AT patients are hypersensitive to ionizing radiation [ 29 ] . Although many reports showed the association of ATM mutation with risk of a number of different human malignancies, including prostate cancer, breast cancer, ovarian cancer, B-cell chronic lymphocytic leukemia and mantle cell lymphoma, the underlying molecular mechanism by which ATM gene causes these changes are not well understood [ 30 31 32 33 34 35 ] . There is so far no study showing the association of ATM gene with any solid tumor.
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