Example sentences for: δ-opioids

How can you use “δ-opioids” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We used C6 glioma cells, transfected to stably express the mouse δ-OR, to examine ERK activation by δ-opioids in a line that does not express the EGFR to confirm our results obtained in the receptor down-regulation experiments.

  • We have shown that δ-opioids increase the phosphorylation of ERKl/2 in HEK-293 cells when the mouse wild type (WT) δ-OR is stably expressed [ 11 13 ] . The concentrations required to observe DSLET-mediated ERK phosphorylation (EC 50 = 10 nM; Figure 1a) are consistent with those reported for other δ-OR-mediated events, including G protein activation and adenylyl cyclase inhibition [ 16 17 ] . Moreover, no change in total ERK expression was observed, concomitantly, with ERK phosphorylation in any of our experiments (data not shown).

  • These results suggest that transactivation of the EGFR does not play a role in δ-OR phosphorylation or ERK activation by δ-opioids.

  • Potential of endogenously expressed insulin receptors (IR) and PDGFR to act as surrogate protein scaffolds during ERK activation by δ-opioids

  • It is possible that these sites can be used as surrogate scaffold proteins during ERK activation, and we explored the possibility that δ-opioids induce the transphosphorylation of these two RTKs.


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