Words similar to α-synuclein

Example sentences for: α-synuclein

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On balance, therefore, there is no direct evidence that parkin controls α-synuclein toxicity by an effect on protein levels within the cell.
Furthermore, parkin does not just prevent α-synuclein toxicity: it is beneficial against several other stresses (discussed in Shen and Cookson 2004), leading to the possibility that this protein protects neurons against more than just the processes implicated in PD.
More generally, we have to bear in mind that whether recessive parkinsonism has anything to do with α-synuclein is still an open question.
One possibility is that by sequestering α-synuclein into this insoluble body and compartmentalizing the potentially toxic species away from possible targets in the cytoplasm, the Lewy body represents an attempt of the cell to protect itself (Olanow et al.
Presumably, neurons require α-synuclein for their normal function and thus cannot simply dispense with this protein that has toxic properties, although mice in which the α- synuclein gene is knocked out have no obvious deficits (see Dauer and Przedborski [2003] for discussion).