Example sentences for: ydxp

How can you use “ydxp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Expression of the Src KMfused to the full length Cas SD, 5' N-terminal YQXP motifs or 3' C-terminal YDXP motifs alone demonstrated that these fusions were not stably tyrosine phosphorylated in cells (Fig.

  • The v-crk SH2 domain interacts with YXXP motifs upon phosphorylation, suggesting that both of these regions may be able to interact with v-crk [ 37 ] . Fusions of the kinase inactive Src kinase domain and either the full Cas SD, the 5' region of the Cas SD (Cas(5'SD), containing 4 YQXP motifs) or the 3' of the Cas SD (Cas(3'SD), containing 9 YDXP motifs), are not stably tyrosine phosphorylated when expressed alone in cells (data not shown and see Fig.

  • Moreover, in the absence of stable tyrosine phosphorylation as seen in the Src kinase inactive fusions, v-crk could either induce their phosphorylation, or protect transiently phosphorylated YDXP motifs from dephosphorylation through yet unknown mechanisms.

  • Using different regions of the Cas SD containing either the YDXP or the YQXP motifs, we could demonstrate that v-crk specifically interacts with the C-terminal YDXP motifs when tyrosine phosphorylated.

  • Thus while both sets of motifs in the Cas SD have been thought to interact with the v-crk SH2 domain, we demonstrated that this domain only interacts with the YDXP motifs.


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