Example sentences for: ydxp

How can you use “ydxp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We transfected v-crk alone or along with the chimera of the attenuated Src kinase domain fused to the C-terminal crk interacting region of the Cas substrate domain (Src*/Cas(3'SD), carrying the YDXP motifs) into Cos-7 cells and immunoprecipitated either the chimera or v-crk and assayed for interacting tyrosine phosphorylated proteins (Fig.

  • S 325to R 516, 9 YDXP motifs) of Cas amplified.

  • These data indicate that the v-crk SH2 domain interacts with the C-terminal YDXP motifs, and as suggested by Birge et al, v-crk may be able to protect them from dephosphorylation and/or induces their phosphorylation [ 12 ] . They also suggest that the YQXP motifs may be involved in binding to other intracellular signaling molecules.

  • We then used the 5' and 3' fusions of the Cas SD to determine which motif, YQXP or YDXP, interacts with the v-crk SH2 domain.

  • Expression of the Src KMfused to the full length Cas SD, 5' N-terminal YQXP motifs or 3' C-terminal YDXP motifs alone demonstrated that these fusions were not stably tyrosine phosphorylated in cells (Fig.


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