Example sentences for: yac

How can you use “yac” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Eight transgene-positive YAC clones were identified among 950 His +5-FOA-resistant transformants screened by PCR for the presence of the zeta-globin promoter sequence (Table 3).

  • Development of the YAC map was described previously by Engle, et al.

  • Probes were selected that flank known sites of genomic rearrangement based upon previous yeast artificial chromosome (YAC) and BAC/PAC mapping studies, together with the human sequence map available from the University of California at Santa Cruz (UCSC) Genome Browser [ 11 12 13 14 15 ] . Probes flanking the Prader-Willi/Angelman syndrome breakpoints, in addition to a characterized inv dup(15) rearrangement were selected to test the possibility that the pericentric inversion evolutionary breakpoint corresponded to a site of known human genomic instability (Figure 1).

  • The resulting YAC does not express URA3 and, therefore, the clone can be selected by medium containg 5-FOA.

  • We selected probes to refine the chimpanzee XVq11-q13 pericentric inversion breakpoint on the basis of YAC maps of human 15q11-q13, in addition to the genome assemblies produced by the Human Genome Project [ 30 31 ] . We chose BACs targeted for complete sequencing (Figure 1) so that the underlying sequence of each probe would be available for further analysis pending comparative FISH results.


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