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Example sentences for: yac

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The size of YAC inserts was determined by clamped homogeneous electrical field gel electrophoresis and visualized with an alphoid DNA probe.
Eight transgene-positive YAC clones were identified among 950 His +5-FOA-resistant transformants screened by PCR for the presence of the zeta-globin promoter sequence (Table 3).
Yeast and bacterial artificial chromosome (YAC and BAC) contigs have been generated and a positional cloning approach to identify the CFEOM1 causative gene is ongoing.
Probes were selected that flank known sites of genomic rearrangement based upon previous yeast artificial chromosome (YAC) and BAC/PAC mapping studies, together with the human sequence map available from the University of California at Santa Cruz (UCSC) Genome Browser [ 11 12 13 14 15 ] . Probes flanking the Prader-Willi/Angelman syndrome breakpoints, in addition to a characterized inv dup(15) rearrangement were selected to test the possibility that the pericentric inversion evolutionary breakpoint corresponded to a site of known human genomic instability (Figure 1).
We also obtained yeast artificial chromosome (YAC) clones covering the interval between the 3' end of GABRG3 and OCA2 (962D11; contig WC-153) and to which an APBA2 EST (Wl-14097) and nearby markers had been mapped (764C6; contig WC-699).