Example sentences for: wtpai-

How can you use “wtpai-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The inhibitory activities of wtPAI-1 and mutants were measured by a direct chromogenic assay using uPA (100 U/μg) and substrate S-2444.

  • So, both Glu351Arg and Glu351Arg are better thrombin inhibitors than wtPAI-1.

  • Mutations at Glu351 may decrease the original repulsive interactions with variable region of thrombin, which may slow the rate of thrombin inhibition, or results in favorable interactions that may not exist when wtPAI-1 react with thrombin.

  • It should be noted that all these mutants could be activated to a similar extent by 6 M Gnd-HCl (~20% inhibitory activity of the wtPAI-1, activated under the same conditions).

  • Moreover, The rate constants of Glu351Ala and Glu351Arg for thrombin inhibition were 2 to 4 folds higher than that of wtPAI-1 and rate constants of Glu351Ala and Glu351Arg to plasmin were 2 fold higher than that of wtPAI-1.


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