Words similar to wortmannin

Example sentences for: wortmannin

How can you use “wortmannin” in a sentence? Here are some example sentences to help you improve your vocabulary:

We found that wortmannin and rapamycin had no effect on basal SP-A mRNA levels, at any concentration tested.
To confirm the inhibitory effect of wortmannin on insulin action, a structurally different PI 3-kinase inhibitor, LY294002, was used.
However wortmannin, at concentrations of 5-200 nM, abolished the insulin-mediated inhibition of SP-A mRNA levels at all concentrations tested (5-200 nM, Fig.
LDH activity was not different from controls in cells treated for 12 to 16 hours with either 200 nM wortmannin, 5 μM LY294002, 20 nM rapamycin, or 10 μM PD98059 (data not shown).
H441 cells resemble bronchiolar epithelial Clara cells in phenotype and produce both SP-A and SP-B mRNA and protein [ 14 ] . The hormonal regulation of SP-A and SP-B gene expression in H441 cells is similar to that observed in differentiated type II cells in human fetal lung explants [ 6 7 15 16 ] . We treated H441 cells with the four inhibitors of signal transduction: wortmannin, LY294002, rapamycin and PD98059, to elucidate which signaling pathways are activated when insulin inhibits SP-A gene expression.