Words similar to wnt-

Example sentences for: wnt-

How can you use “wnt-” in a sentence? Here are some example sentences to help you improve your vocabulary:

Even though Wnt-1 has not been directly implicated in human cancers, many components of the Wnt signaling pathway (such as β-catenin, APC, c-myc, and cyclin D 1) are involved in human tumors including breast cancer [reviewed in ref.
In order to produce such a model for studying the effects of Pten mutations in breast cancer, we have crossed Wnt-1 TG mice to mice heterozygous for Pten . Mice transgenic for MMTV- Wnt-1 and heterozygous for Pten developed mammary adenocarcinomas much earlier than mice carrying either lesion alone.
LiCl has previously been shown to mimic activation of Wnt-1 signaling by stabilizing beta-catenin through its inhibition of glycogen synthase kinase-3β (GSK-3β), a kinase that phosphorylates beta-catenin and promotes its degradation via the ubiquitin proteasome pathway [ 39 ] . C57mg cells treated with LiCl exhibited elevated levels of mesothelin but not SL-1 (Figure 2, left panel).
After a mutant allele of Pten was crossed into Wnt-1 TG mice, we found that ductal carcinomas appeared earlier than either alteration alone and that LOH at the Pten locus occurred in the majority of these tumors, suggesting a selective growth advantage in cells that lack Pten functions.
Most Wnt-1 TG mice (38/49) developed only one palpable tumor regardless of Pten status.