Example sentences for: wnt-

How can you use “wnt-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A recent report demonstrated that Wnt-5a and Rfz-2 can induce the nuclear localization of the transcription factor NF-AT [ 14 ] . Their results show that NF-AT is a downstream target of the Wnt/Ca 2+pathway and antagonizes the Wnt/beta-catenin pathway in Xenopus embryos.

  • However, tumors in Wnt-1 TG mice in a wild type Pten background already have highly suppressed apoptosis and accelerated proliferation rates, and any incremental changes, if present, may be difficult to detect with our current assays.

  • In initial experiments, we found that Wnt-3A protein elevates the levels of β-catenin 5-10 fold (Figure 4); and that a transiently transfected TCF reporter construct is activated 3-4 fold (not shown).

  • We compared the Wnt-5a/Rfz-2 expression profile to the Wnt-1 expression profile to rule out genes common in both pathways and to identify those genes specific to Wnt-5a and Rfz-2.

  • To date, heterozygous inactivation of any of the other tumor suppressor genes implicated in breast cancer, including P53, Brca1, Brca2 , and Rb , has failed to cooperate with Wnt-1 in promoting the appearance of mammary tumors [reviewed in ref.


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