Example sentences for: wnt

How can you use “wnt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The secreted glycoproteins in the Wnt/Wingless (Wg) family serve diverse functions in developmental processes, ranging from cell fate specification and cell proliferation to cell migration and cell polarity [ 1 2 ] , and deregulation of the Wnt signaling pathway can lead to cancer [ 3 4 ] . In a simplified model of the canonical Wnt/β-catenin signaling pathway, the binding of Wnts to their receptors activates a downstream component, Dishevelled (Dsh).

  • Furthermore, it was reported that LRP signaling can be activated in a Dsh - independent fashion [ 14 ] . These data suggest that Wnt/Wg could signal through LRP directly to the β-catenin destruction complex in a Fz- and Dsh-independent fashion.

  • In order to evaluate the transcriptional activity of FLAG epitope-tagged β-catenin in a medulloblastoma cell line, the S37F and wild-type constructs were introduced into DAOY cells along with the Wnt pathway TOPFLASH reporter.

  • However, when the time courses of Wnt- and BMP-induced gene expression were compared, it appeared that BMP-4 acts as soon as at 30 minutes, but that Wnt takes 2 hours to have an effect (Figure 3).

  • The lack of aberrant neuronal proliferation in our mice suggests that differentiated neurons may not be as susceptible to the mitogenic effects of Wnt signaling as are neuroepithelial progenitor cells [ 22 ] .


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