Words similar to wnt
Example sentences for: wnt
How can you use “wnt” in a sentence? Here are some example sentences to help you improve your vocabulary:
The secreted glycoproteins in the Wnt/Wingless (Wg) family serve diverse functions in developmental processes, ranging from cell fate specification and cell proliferation to cell migration and cell polarity [ 1 2 ] , and deregulation of the Wnt signaling pathway can lead to cancer [ 3 4 ] . In a simplified model of the canonical Wnt/β-catenin signaling pathway, the binding of Wnts to their receptors activates a downstream component, Dishevelled (Dsh).
Furthermore, it was reported that LRP signaling can be activated in a Dsh - independent fashion [ 14 ] . These data suggest that Wnt/Wg could signal through LRP directly to the β-catenin destruction complex in a Fz- and Dsh-independent fashion.
In order to evaluate the transcriptional activity of FLAG epitope-tagged β-catenin in a medulloblastoma cell line, the S37F and wild-type constructs were introduced into DAOY cells along with the Wnt pathway TOPFLASH reporter.
However, when the time courses of Wnt- and BMP-induced gene expression were compared, it appeared that BMP-4 acts as soon as at 30 minutes, but that Wnt takes 2 hours to have an effect (Figure 3).
The lack of aberrant neuronal proliferation in our mice suggests that differentiated neurons may not be as susceptible to the mitogenic effects of Wnt signaling as are neuroepithelial progenitor cells [ 22 ] .
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