Words similar to wnt
Example sentences for: wnt
How can you use “wnt” in a sentence? Here are some example sentences to help you improve your vocabulary:
LRPs have been shown to bind to Wnt/Wg through the first and second EGF repeats of their extracellular domain [ 11 ] . Our unpublished work in mammalian cells and results from others [ 11 13 ] demonstrate that the expression of LRP6 or an aminoterminal truncation mutant (LRP6ΔN), which should no longer bind to Wnt, can activate the Wnt signaling pathway.
Turcot's syndrome is caused by germline mutations in the gene APC , a member of the Wnt signaling pathway.
In contrast, cycloheximide did not block induction of target genes by BMP (Figure 4), the mechanism of which does not involve protein accumulation [ 12 ] . These findings underscore the importance of β-catenin protein elevation in the response to Wnt.
The greatly increased incidence of medulloblastomas in patients inheriting mutations in the APC tumor suppressor gene suggests that activation of Wnt signaling could be sufficient in some cases to initiate medulloblastoma formation.
The overall pattern of gene expression observed in response to Wnt has important implications for the role of Wnt signaling in development and cancer.