Example sentences for: wnt

How can you use “wnt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the absence of a Wnt signal, GSK3 phosphorylates β-catenin, which then becomes targeted for degradation [ 6 ] . The binding of Wnt to its receptors initiates a cascade of events that inhibit GSK3 and ultimately prevent degradation of β-catenin.

  • Wnt activation in the adult hippocampus, cortex and cerebellum did not result in tumors or other CNS malformations.

  • Consequently, the level of cytoplasmic β-catenin rises, and stabilized β-catenin, together with the transcriptional factor LEF/TCF, regulates the transcription of Wnt target genes.

  • LRPs have been shown to bind to Wnt/Wg through the first and second EGF repeats of their extracellular domain [ 11 ] . Our unpublished work in mammalian cells and results from others [ 11 13 ] demonstrate that the expression of LRP6 or an aminoterminal truncation mutant (LRP6ΔN), which should no longer bind to Wnt, can activate the Wnt signaling pathway.

  • Depletion of Wnt protein


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