Words similar to wnt
Example sentences for: wnt
How can you use “wnt” in a sentence? Here are some example sentences to help you improve your vocabulary:
This patterning appears to involve the interaction of various signaling factors, including FGF, BMP, WNT, and retinoic acid, all of which act as posteriorizing factors (Kudoh et al.
Whether Wnt target gene activation is cycloheximide sensitive has never been tested however.
Depletion of Wnt protein
APC mutations have been identified in medulloblastoma cell lines and up to 4% of sporadic medulloblastomas [ 16 17 ] . Furthermore, point mutations or small deletions in β- catenin exon 3 have been identified in 5-10% of sporadic medulloblastomas and in supratentorial primitive neuroectodermal tumors (PNETs) [ 17 18 19 ] . Finally, large deletions in AXIN were recently found in 12% of sporadic medulloblastomas [ 20 ] . In the absence of Wnt signaling β-catenin is sequestered in the cytoplasm, and nuclear translocation of β-catenin has been used to monitor activation of the Wnt pathway in a number of different tumor types.
The observation that LRP5ΔN activates the Wnt/Wg signaling pathway in a Dsh-independent manner [ 14 ] , and our data with overexpressed LRP6ΔN and LRP6, further support this proposal.
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