Words similar to villi
Example sentences for: villi
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When compared to chorionic villi, trophoblast cultures showed stronger ~59 and 48 kDa species, characteristic for cultured fibroblasts.
Western blot analysis of placental villi and trophoblast cultures indicates that cultured trophoblast cells show additional bands, including ~170 kDa species, possibly an LHR homodimer [ 19 ] . Although the ~170 kDa species persisted in late cultures, other (additional) LHR variants diminished.
In contrast, vascular LHR expression was detected in sinusoids of chorionic villi from normal term placentae, but was virtually absent in all abnormal placentae.
As recently indicated [ 30 ] , certain types of placental abnormality have also been ascribed to the villous immaturity (low or no Thy-1 differentiation protein expression in placental villi and a lack of blood sinusoid dilatation - PT4, see above) accompanied by an existing (diabetes mellitus) or absent placental hypertrophy (intrauterine growth retardation) - Table 1. However, it has been suggested that although chronic placental adaptations may be successful for the fetal survival, e.g. in placental senescence or maternal diabetes, they may lead to adverse outcomes later in the life of an individual [ 22 ] . Therefore, although it might not be apparent in the newborn, the abnormal placenta may indicate a burden for the future of an individual and for the quality of the human population.
We also utilized frozen blocks and protein extracts from human placental chorionic villi, and protein extracts from trophoblast cultures and cultured amniotic fibroblasts and placental mononuclear cells [ 46 ] . Placental mononuclear cells were collected from the first digestion, which contains no trophoblast cells [ 46 ] . The study was approved by the Institutional Animal Care and Use Committee and Institutional Review Board.
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