Example sentences for: vertebro-basilar

How can you use “vertebro-basilar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Functional activation by visual stimulation was chosen to examine the vertebro-basilar diathesis of Fabry disease.

  • Previously, in Fabry disease, we have reported resting cerebral hyper-perfusion in a predominantly vertebro-basilar distribution together with abnormalities of vascular nitrotyrosine staining.

  • However, the more generalized cerebrovascular response noted in both the carotid and vertebro-basilar circulation suggests stimulus spread in Fabry disease, possibly due to a decreased response threshold in non-visual cortex vasculature.

  • A similar vascular hyper-responsiveness has been noted in caveolin-1 knock-out mice [ 25 26 ] raising the possibility that the accumulation of Gb 3 results in over-activity of uncoupled endothelial nitric oxide synthase within endothelial cell caveolae generating superoxide and other reactive oxygen species [ 27 ] . The latter may have a vasodilatatory effect [ 28 ] . Predominance of vascular abnormalities in the vertebro-basilar system in Fabry disease suggests fundamental biologic differences between the anterior and the posterior circulation.

  • Such difference might, for example, result from the neural crest origin of pericytes and vascular smooth muscle in the anterior circulation as opposed to paraxial mesoderm in the vertebro-basilar or posterior circulation [ 29 ] .


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