Words similar to vaccinia
Example sentences for: vaccinia
How can you use “vaccinia” in a sentence? Here are some example sentences to help you improve your vocabulary:
035, chi-square test on crude data), with, for example, 30% of those reporting having carefully read it listing transmission of vaccinia to family or friends as their principal concern, compared to 17%-26% of the groups reading the vaccine information sheet less carefully or not at all.
Priming with various types of "live" expression followed by boosting with purified subunits is currently favored as a method to obtain stronger immunologic responses that either method alone [reviewed in [ 1 ] and [ 2 ] ]. Previously acquired immunity to a viral vector such as vaccinia may influence its efficacy in inducing immunity against heterologous proteins being delivered [ 16 17 18 19 ] and it may be wise to provide physicians with HIV vaccines based on a variety of vectors to handle a variety of clinical situations.
Use of vaccinia vectors in humans is problematic, especially in areas where HIV infection is common—immune-suppressed individuals can develop serious skin lesions—and several alternative vaccines based on other vectors as well as harmless vaccinia ones are under development.
Moreover, the functional viral RdRP, as detailed later for RSV, is a complex holoenzyme composed of viral as well as cellular proteins [ 17 18 19 20 21 22 23 ] . Second, many NNR viral genomes and proteins are currently expressed from vaccinia-based cDNA clones, which generally requires superinfection by vaccinia virus [ 22 23 ] . Unfortunately, vaccinia virus itself is a major modulator of cellular signaling, including MAP kinase pathways and the actin cytoskeleton [ 24 25 26 ] . It is, therefore, virtually impossible to study the interaction between cellular signaling pathways and NNR viruses in cells that are also superinfected by vaccinia virus [ 24 25 26 ] . Third, mutations in the recombinant DNA are "permanent", and thus, the mutational phenotype cannot be switched on at pre-determined time points in infection.
In the present study, we have investigated the potential of porphyrins (Por) and phthalocyanines (Pc) to prevent infection by vaccinia virus in cell culture.
Loading...