Words similar to vaccinia
Example sentences for: vaccinia
How can you use “vaccinia” in a sentence? Here are some example sentences to help you improve your vocabulary:
Two strains of vaccinia virus (VV) were used in this study: the Western Reserve (WR) and International Health Department-J (IHD-J) strains.
This range is comparable to that observed for other compounds active against vaccinia.
Use of vaccinia vectors in humans is problematic, especially in areas where HIV infection is common—immune-suppressed individuals can develop serious skin lesions—and several alternative vaccines based on other vectors as well as harmless vaccinia ones are under development.
In the current study, inhibition of vaccinia infection is not due to photoactivation of the tetrapyrroles, as shown by two aspects of the experiments.
Moreover, the functional viral RdRP, as detailed later for RSV, is a complex holoenzyme composed of viral as well as cellular proteins [ 17 18 19 20 21 22 23 ] . Second, many NNR viral genomes and proteins are currently expressed from vaccinia-based cDNA clones, which generally requires superinfection by vaccinia virus [ 22 23 ] . Unfortunately, vaccinia virus itself is a major modulator of cellular signaling, including MAP kinase pathways and the actin cytoskeleton [ 24 25 26 ] . It is, therefore, virtually impossible to study the interaction between cellular signaling pathways and NNR viruses in cells that are also superinfected by vaccinia virus [ 24 25 26 ] . Third, mutations in the recombinant DNA are "permanent", and thus, the mutational phenotype cannot be switched on at pre-determined time points in infection.
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