Words similar to tyrp-

Example sentences for: tyrp-

How can you use “tyrp-” in a sentence? Here are some example sentences to help you improve your vocabulary:

Clinically, TYRP-1 is thought to be important as a melanoma antigen that is highly antigenic to cytotoxic T cells, providing a potential target for melanoma vaccine development [ 16 ] . TYRP-1 appears to be less expressed in advanced primary lesions and metastases of human cutaneous melanoma and uveal melanoma [ 32 ] . Primary melanoma samples express TYRP-1 transcripts at higher levels than melanoma metastases [ 33 ] , and IHC analysis of malignant melanocytic lesions has shown that the invasive cells of primary melanomas are TYRP-1-negative [ 34 ] .
However, IHC reveals that TYRP-1 protein staining is easily detectable in many samples.
The aim of the present work was to examine the cellular distribution of OPN, of TSP-1 and of TYRP-1 in human breast tissue, and to determine whether the relative expression level of these three genes was associated with malignancy or breast tumor metastasis.
The sequences of the PCR primer pairs used for each gene are as follows: TYRP-1, 5'-GATGGCAGAGATGATCGGGA-3' and 5'-AGAAATTGCCGTTGCAGTGAC-3' ; TSP-1, 5'-CAGCAGCCGCTTTTATGT-3' and 5'-CCGAGTATCCCT-GAGCCCTC-3' ; OPN, 5'-TTGCAGCCTTCTCAGCCAA-3' and 5'-GGAGGCAAAAGCAAATCACTG-3' ; and GAPDH, 5'-CCACCCATGGCAAATTCC-3' and 5'-GGGATTTCCATTGATGACA-3'.
TYRP-1 is a type I membrane protein expressed by melanomas and normal melanocytes that was originally characterized as an oxidase in the melanin biosynthetic pathway.