Example sentences for: tumor-infiltrating

How can you use “tumor-infiltrating” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Previous studies using lethal dose radiation and bone marrow transplant prior to CD4 +T cell transfer in another Rip-Tag line of mice indicated that such treatment could produce a modest increase in the number of tumor-infiltrating T cells [ 22 ] . The current study extends the thesis by focusing on the use of sub-lethal radiation to enhance the anti-tumor immunity of adoptively transferred tumor-antigen-specific lymphocytes in Rip1-Tag2 mice.

  • Thus, it is possible that some of the tumor-infiltrating, CD4 +T cells may recognize targets other than Tag.

  • This may be the result of the "bystander" effects induced by the tumor-infiltrating, Tag-specific, CD4 +T cells.

  • B7-1) on tumor cells [ 45 ] . Radiation has been shown to increase the expression of MHC class I and II molecules in tumor cell lines [ 46 47 ] . Thus, the tissue damage signals evoked by ionizing radiation may trigger the activation and infiltration of antigen-presenting cells, in particular dendritic cells [ 38 48 49 50 ] . Indeed, in the regression study, we observe some increase of tumor-infiltrating dendritic cells in the group receiving the single radiation treatment.

  • It is possible that radiation-induced, tumor-infiltrating dendritic cells may facilitate sustained activation and infiltration of the adoptively transferred CD4 +T cells in solid tumors in the combination group.


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