Words similar to ttp

Example sentences for: ttp

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The ability of LPS to induce TTP independently of TNF may account for the earlier response observed in neutrophils and monocytes that have LPS-signaling transduction molecules.
Both alpha- and gamma-tocopherol are absorbed from the intestine and secreted into chylomicrons equally well [ 6 7 ] . The selective retention of alpha-tocopherol in plasma is attributed to a number of factors such as the hepatic alpha-tocopherol transfer protein (alpha-TTP), which preferentially incorporates alpha-tocopherol (over gamma-tocopherol) into very low density lipoprotein [ 8 9 10 ] . Indeed, the affinity of the different forms of vitamin E for the alpha-TTP protein appears to be a primary determinant of their plasma levels [ 8 ] . In addition, there is evidence suggesting that gamma-tocopherol is preferentially catabolized to a water-soluble form (2,7, 8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman or gamma-CEHC) by side chain oxidation [ 11 12 ] .
Although the initial rise in TTP in vivo paralleled a rapid and considerable increase in plasma TNF, the second, late increases in intracellular TTP did not reflect TNF levels.
Induction of TTP in the THP-1 cell line
Since TNF biosynthesis in macrophages is rapidly triggered by treatment with LPS, the effects of this endotoxin on TTP expression were examined.