Words similar to truncation

Example sentences for: truncation

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The highly acidic carboxy-terminal (BRCT) region of BRCA1 has been suggested to play a role in transactivation [ 11 ] . BRCT interacts with BRCA2, Rad51, other tumor suppressing elements, as well as numerous transcription factors, such as RNA helicase A and STAT1 [ 15 16 ] . Recently, it has been discovered that truncation of this region resulted in suppression of apoptosis following pro-apoptotic stimuli [ 17 ] . Further, these studies also suggested that the BRCT region facilitates apoptotic functions within the caspase pathway.
The relatively high proline content of this additional sequence and the positioning of this truncation would be expected to disrupt the second half of the coiled-coil region of the protein.
N-terminal truncation studies showed the C-terminal 37% to 45% of the BTBD proteins are sufficient for binding TOP1.
Removal of 10-13 residues from the C terminus of PP5 results in a highly active enzyme that is only modestly stimulated by lipid [ 19 ] . To examine the role of the C terminus in controlling Ppt1p phosphatase activity, a similar truncation mutant, Ppt1p (1-504), was expressed and characterized (Fig.
The YbaK fold is related to a circular permutation and truncation of the C-lectin fold.