Example sentences for: truncation

How can you use “truncation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The highly acidic carboxy-terminal (BRCT) region of BRCA1 has been suggested to play a role in transactivation [ 11 ] . BRCT interacts with BRCA2, Rad51, other tumor suppressing elements, as well as numerous transcription factors, such as RNA helicase A and STAT1 [ 15 16 ] . Recently, it has been discovered that truncation of this region resulted in suppression of apoptosis following pro-apoptotic stimuli [ 17 ] . Further, these studies also suggested that the BRCT region facilitates apoptotic functions within the caspase pathway.

  • However, the major truncation of the midasin N-terminal domain in Giardia (Fig.

  • LRPs have been shown to bind to Wnt/Wg through the first and second EGF repeats of their extracellular domain [ 11 ] . Our unpublished work in mammalian cells and results from others [ 11 13 ] demonstrate that the expression of LRP6 or an aminoterminal truncation mutant (LRP6ΔN), which should no longer bind to Wnt, can activate the Wnt signaling pathway.

  • will be lessened, but not eliminated, because the targets are more likely to be near the real 3' ends of the mRNAs The truncation that results from amplifying samples means that the same protocol should be used for all samples in a given study.

  • In contrast, C-terminal truncation of PP5 activates the enzyme as extensively as lipid treatment, and little further activation is seen with lipid [ 19 ] . In the case of PP5, subtilisin digestion removed both the TPR domain and the C terminus [ 19 ] . The observation that C-terminal truncation increased Ppt1p activity toward both 32P-casein and 32P-MBP, but subtilisin digestion increased activity only toward 32P-MBP (see Fig.


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