Words similar to truncated

Example sentences for: truncated

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It was previously suggested that the peri-centromeric targeting of C/EBPα was a function of DNA binding: C/EBPα binding sites are concentrated within the repeated DNA sequences that comprise the bulk of peri-centromeric chromatin [ 49 ] . Indeed, C/EBPα truncated to contain little more than the DNA binding, bZIP domain still concentrated at peri-centromeric chromatin [ 45 ] . By contrast, C/EBPα deleted of amino acids 310 to 358 (Fig.
Germline mutations that cause breast and ovarian cancer predisposition frequently result in truncated and presumably inactive BRCA1 protein [ 12].
To investigate this, we segregated our set of L1s with TSDs into the following major classes of structural variants and analyzed their respective TSDs: 5' truncated, 5' inverted, or full-length (L1 start ≥ 10) standard insertions, and 3' transduction candidates (Figure 1b).
Thus, serovar B lacks TrpEa altogether, serovars A and C express severely truncated TrpEa proteins, whereas serovars D and L2 express full-length TrpEa proteins (although undoubtedly inactive).
We describe here three new transgenic (Tg) mouse lines in which expression of human CAR with a truncated cytoplasmic domain (hCARΔcyt) is limited to thymocytes and lymphocytes under direction of a human CD2 mini-gene [ 16 ] . The three lines are similar in having transgene expression restricted to the lymphoid lineage, but differ in the pattern of hCARΔcyt expression profiles within lymphoid populations.