Example sentences for: trigger

How can you use “trigger” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Compromised ER function (induced by numerous stressors including depletion of ER calcium stores) may lead to the accumulation of unfolded proteins in the ER [ 11 ] . These events may trigger the UPR, in which the transcription of genes encoding ER-resident chaperones is upregulated.

  • Second, radiation-induced damage or abnormality may induce a "tissue damage signal" in the solid tumors through radiation-mediated apoptosis [ 38 ] . There is mounting evidence that apoptotic cell death is not immunologically benign, but can trigger immune responses [ 39 40 ] . For example, cells treated with ultraviolet radiation can provide potent adjuvant function in vivo [ 41 ] . Sub-lethal radiation could result in altered expression of pro or anti-inflammatory chemokines [ 42 43 44 ] or increased expression of T cell co-stimlulatory molecules (i.e.

  • Cigarette smoke has also been considered a major player in the pathogenesis of asthma and as a trigger for acute symptoms [ 2 ] . Exposure to cigarette smoke activates an inflammatory cascade in the airway epithelium resulting in the production of a number of potent cytokines and chemokines, with accompanying damage to the lung epithelium, increased permeability, and recruitment of macrophages and neutrophils to the airway [ 3 ] . Even brief exposure to cigarette smoke has been shown to increase expression of IL-8 in primary cultures of human bronchial epithelial cells (HBEs) in the presence of dust mite allergen [ 4 ] . Increased release of the chemokine IL-8 has also been shown for cultured HBEs exposed to cigarette smoke extract (CSE) [ 5 6 ] and diesel exhaust particles [ 7 ] . However, the precise molecular events that bring about these intracellular changes and acute inflammation in lung epithelial cells are not well understood.

  • A nostalgia fest for the Singing Cowboy, with obituaries declaring him a "soothing presence" (Mike Clark and David Zimmerman, USA Today ) and "that almost unimaginable thing, the domestic cowboy" (the New York Times ). Critics harp on his loyalty to wife Dale and horse Trigger and his tendency to express himself through ballads, not fisticuffs.

  • Two organ systems - the gastric lining of the GI tract, and the area postrema (the chemoreceptor trigger zone), the vestibular apparatus, and the cortex of the brain are important contributors [ 54 ] .


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