Example sentences for: transmembrane

How can you use “transmembrane” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Signal peptides were predicted using the SIGNALP program [ 33, 34] and the transmembrane regions were predicted using the TOPRED program [ 35].

  • Polyclonal rabbit antisera were prepared using synthetic peptides corresponding to the intracellular transmembrane portions of the types IA, IB, and II BMPRs [ 10].

  • The mutagens permit direct selection of clones in which cellular genes have been disrupted and simplify the characterisation of genes associated with recessive mutations [ 1 ] . Mutagenesis of embryo-derived stem (ES) cells, coupled with in vitro genetic screens, has been widely used to analyse gene functions in mice [ 1 ] . These have included screens for mutations in developmentally regulated genes [ 2 3 4 5 ] , in genes regulated by extracellular agonists [ 6 7 ] , and in genes encoding secreted and transmembrane proteins [ 8 9 ] . Characterized mutations include genes involved in intracellular trafficking [ 10 ] , transcriptional regulation [ 11 12 ] , signal transduction [ 7 8 11 13 14 15 ] , neural development [ 16 ] and neural wiring [ 17 ] , and axial patterning [ 18 19 ] . The rapid expansion of the nucleic acid databases has had a tremendous impact on the identification of genes disrupted by gene entrapment.

  • Positions of transmembrane domains in ORs were predicted using the PHD topology routine [ 77] at PredictProtein server at EMBL, Heidelberg [ 78].

  • These included the predicted signal sequences and transmembrane domains and a striking conservation surrounding a possible protease cleavage site in the proteins that likely serve as envelope fusion proteins [ 7].


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