Example sentences for: tox

How can you use “tox” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In addition, LCP1 is more highly expressed than Tox in skin, consistent with isolation of LCP1 from Langerhans cells.

  • The asparagine at position 10 makes contact with DNA in the hSRY-DNA complex [ 24 ] , as does the serine at this position in the NHP6A-DNA complex [ 7 ] . A hydrophobic residue at position 32 that can partially intercalate into DNA plays a role in DNA binding of some sequence-independent HMG-box proteins [ 7 25 26 ] . Position 32 is the hydrophobic residue phenylalanine in TOX, in contrast to the polar residues found at this position in SRY, SOX proteins and LEF-1.

  • Based on sequence alignment comparison with other previously characterized HMG-box proteins, we predict that the TOX HMG-box subfamily will likely fall into the sequence-independent category of HMG-box proteins.

  • Tox is the murine homologue of the human gene KIAA0808, previously isolated from brain tissue [ 29 ] . TOX and KIAA0808 are approximately 90% identical at both the nucleotide and amino acid level [ 15 ] . Using BLAST program searches [ 30 31 ] we have now identified 3 other murine genes that are predicted to encode proteins that have nearly identical HMG-box sequences to TOX (Fig.

  • Similarly, TOX is more closely aligned with the sequence-independent HMG-box proteins than the sequence-specific transcription factors at position 65.


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