Words similar to tox
Example sentences for: tox
How can you use “tox” in a sentence? Here are some example sentences to help you improve your vocabulary:
In addition, three other predicted proteins share almost identical HMG-box domains with TOX, defining a new subfamily of HMG-box proteins.
This 8 amino acid insertion is not found in other TOX subfamily members or the human homologue C20ORF100, and can be explained by an error in the automated computer prediction of the end of the relevant exon.
The TOX subfamily is highly conserved in mice and humans, and is distributed on four separate chromosomes.
The asparagine at position 10 makes contact with DNA in the hSRY-DNA complex [ 24 ] , as does the serine at this position in the NHP6A-DNA complex [ 7 ] . A hydrophobic residue at position 32 that can partially intercalate into DNA plays a role in DNA binding of some sequence-independent HMG-box proteins [ 7 25 26 ] . Position 32 is the hydrophobic residue phenylalanine in TOX, in contrast to the polar residues found at this position in SRY, SOX proteins and LEF-1.
This is intriguing considering that both mosquito and fly species belong to the same taxonomic order (Diptera), and diverged approximately 250 million years ago, as compared to the 450 million years separating pufferfish and humans [ 45 ] . It has been noted that only half the genes in the Drosophila and Anopheles genomes can be interpreted as homologues [ 46 ] . We have identified a 250 amino acid protein (CG12104-PA) in the Drosophila database, which contains a partial HMG-box motif with weak similarity to the TOX family.
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