Example sentences for: tnfr

How can you use “tnfr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • No appreciable sequence homology was seen between either of the natural ligands, TNFα or TNFβ, and KcF12 although the spacing of cysteine loop was close to that seen in the cysteine rich domains of TNFR2 [ 29 ] . At present, it is not known whether these structural elements play a role in binding of the peptides to TNFR2 and it may be that the peptides mimic rather than recapitulate the contact domains of the natural ligands.

  • Since Tnfrh1 encodes a receptor in the TNFR family lacking a cytoplasmic domain (i.e.

  • In addition, the HSPLs were specific for TNFR2 unlike the native ligands TNF-α and TNF-β which bind to both receptors.

  • It has been previously reported that TNFα induced a TNFR2-specific proliferation of the neuroblastoma cell line SK-N-BE [ 30 ] . KcF12, KcC7 and KcF6 inhibited the proliferative response to TNF-α in this cell line indicating that they could act as antagonists (data not shown).

  • Overall, these data indicate that the surface topology of the TNFR2 binding site is very complex and may be composed of multiple hotspots capable of different regulatory functions.


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