Words similar to tnfr

Example sentences for: tnfr

How can you use “tnfr” in a sentence? Here are some example sentences to help you improve your vocabulary:

While TNFα binds equally well to both receptors, the majority of biologic responses attributed to TNF are mediated via TNFR1 although there is evidence that activation of TNFR2 is responsible for some adverse effects of TNFα [ 19 20 21 22 23 24 ] . Thus, the differential regulation of these two receptors may require drugs that specifically target either TNFR1 or TNFR2 allowing therapeutic efficacy without the expected toxicity profile.
These findings suggest that TNFR2 has multiple biological functions.
In addition, mice with the double deletion of TTP and TNF receptor (TNFR)-1 do not manifest the aggressive inflammation observed in TTP-deficient mice.
Overall, these data suggest that activation (agonism or cytotoxicity) of TNFR2 is mediated through unique hotspots on the receptor that can be defined by the peptides.
Briefly, cells were first treated with a human TNFR1 blocking mAb, mAb225 (10 ug/ml), for at least 30 min at 37 C prior to the addition of agents.