Example sentences for: tmcs
How can you use “tmcs” in a sentence? Here are some example sentences to help you improve your vocabulary:
On the basis of comparative structural predictions of all mammalian TMCs we propose a basic topology of the generic TMC protein with variable intracellular amino- and carboxyl-termini, a conserved core with eight membrane-spanning domains, and some variability in the length of several intra- and extracellular loops (Figure 2).
The TMC protein family has eight members in vertebrates and forms three subfamilies, A, B, and C. TMCs are proteins with a conserved core of eight membrane-spanning domains.
Whereas the genome of Fugu rubripes is one order of magnitude shorter than the length of the human genome, the total number of genes is estimated to be approximately the same [ 8 9 ] . Because of the low homology of amino- and carboxyl-terminal sequences, we were not able to determine the complete coding sequences of the eight pufferfish TMC proteins unequivocally; nevertheless, we obtained sufficient sequence information of the central parts of the proteins bearing the transmembrane domains to classify the eight pufferfish TMCs into the three subfamilies.
Second, our analysis of the organization of vertebrate TMC genes implied identical allocation of the individual TMCs (Figure 3and additional file 1).
All other capitalized amino acids are conserved in more than 70% of all TMCs, and lower case letters indicate the most probable amino acid residue.
Loading...