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Example sentences for: timps

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This chemokine belongs to the CC chemokine family and stimulates Coll I production both by lung fibroblasts taken from areas of inflammation [ 26 ] and in kidneys that suffer from crescentic nephritis [ 45 ] . The former investigators reported that MCP-1 increases collagen accumulation not by decreasing the levels of the collagenase MMP-1, but by stimulating the production of TGFβ1, a well-known stimulator of collagen expression and expression of TIMPs, the natural inhibitors of MMPs.
A further degree of regulation of MMP activity is afforded by the family of inhibitors: tissue inhibitors of metalloproteinases (TIMPs) [ 28].
With the exception of serum MMP-2, which was not elevated over normal, serum levels of all of the other MMPs and TIMPs were elevated to varying degrees, and were not predictive of erosive disease.