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Example sentences for: timp-

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Further studies of IL-4-mediated regulation of this and other genes in cluster A, such as those for PAI-1 and TIMP-1, and in cluster E, such as angiotensin I-converting enzyme (ACE), tyrosine kinase receptor (TEK), and leukemia inhibitory factor receptor (LIF-R), are warranted on the basis of the microarray results presented here.
In contrast, the expression of TIMP-2, an inhibitor of MMP-2, was lower in the RA than in the non-RA samples (25 ± 12 versus 39 ± 9 cells/HPF; P = 0.01).
Pro-MMP-2 complexed with TIMP-2 binds to a TIMP-2 binding site on the membrane-bound MMP-14 receptor, and through a conformational change the catalytic domain becomes exposed forming the active enzyme complex.
Comparisons of tissue levels of MMP-2, MMP-9, MMP-14, and TIMP-2
The RA samples tended to have the highest expression levels of MMP-2 and MMP-14, but they exhibited low levels of TIMP-2 expression.