Example sentences for: timp-

How can you use “timp-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, the activity of MMP-2 is regulated locally by a delicate balance between MMP-14 activation and TIMP-2 inhibition.

  • Synovial tissue expressions of MMP-2, MMP-14, and TIMP-2 were virtually undetectable in all normal volunteers; MMP-9 expression was observed in an isolated area of one normal synovial tissue sample.

  • Pro-MMP-2 complexed with TIMP-2 binds to a TIMP-2 binding site on the membrane-bound MMP-14 receptor, and through a conformational change the catalytic domain becomes exposed forming the active enzyme complex.

  • This may reflect augmented activation of MMP-2 by the relatively high levels of MMP-14 and low levels of TIMP-2 seen in these tissues.

  • Expressions of MMP-2, MMP-9, MMP-14, and TIMP-2 in representative locations in the synovial tissue specimens are shown in Figure 2. Of note, the antibodies used to detect MMP-2 recognized only the latent zymogen form.


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