Words similar to thdp

Example sentences for: thdp

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2) with a first saturation in the submicromolar range (described below) and a second at much higher concentrations of ThDP.
There is a high degree of amino acid similarity among folate transporters and the thiamine transporter of the plasma membrane [ 7 8 9 10 ] . Recently, it was found that in murine cells there can be a substantial efflux of ThDP mediated by the reduced folate carrier protein [ 22 ] . GlyB cells are a Chinese hamster ovary cell line derivative that are deficient in the transport of folates into mitochondria, and the responsible mitochondrial transporter has recently been identified and its gene cloned [ 23 ] . We wondered if the mitochondrial folate transporter was responsible for uptake of ThDP into mitochondria, making analogies to the ability of the plasma membrane folate transporter being able to transport ThDP.
Upon entry into a cell, thiamine is rapidly diphosphorylated to ThDP, resulting in a low intracellular thiamine concentration [ 4 17 ] . The K
The final entry in table 1is for ThDP uptake by mitochondria isolated from glyB cells.
The amount of labeled thiamine or ThDP taken up by the mitochondria was determined by scintillation counting.