Words similar to tfiid

Example sentences for: tfiid

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TFIID acts as a “landing pad” for other GTFs and RNAPII to nucleate PIC assembly.
Taken altogether, the above results show that the intracellular level of TBP and TAF II 135 and consequently TFIID is significantly reduced in differentiated cells through T-RA-induced proteolytic degradation.
These results reveal a novel pathway controlling the intracellular levels of these two TFIID components and show that in F9 cells RA not only induces targeted proteolysis of the RARγ2, but also of the basal transcription factors which mediate transcriptional activation.
RNA polymerase II (pol II) transcription factor TFIID comprises the TATA-binding protein (TBP) and a set of TBP-associated factors (TAF II s) [ [ 1 2 3 ] ]. At least 12 TAF II s have been identified in TFIID and cloning of their cDNAs has shown an evolutionary conservation of TAF II s from yeast to mammals [ [ 4 5 6 7 ] ]. TAF II s are not only components of the TFIID complex, but a subset of TAF II s are also found in the SAGA, PCAF, TFTC/STAGA complexes which lack TBP [ [ 8 9 10 11 12 ] ].
II 135 and consequently TFIID are reduced in differentiated cells through selective proteolysis.