Example sentences for: tecs

How can you use “tecs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In order to investigate the regulation of thymocyte development by TECs, we are studying Hoxa3 +/- Pax1 -/-compound mutant mice.

  • Cytokines produced by TECs are good candidates for mediating at least some of these changes in thymocyte proliferation and apoptosis in the Hoxa3,Pax1 compound mutants.

  • Our results provide direct genetic evidence for these functions of TECs, by showing that these processes are defective in mutants with a primary TEC differentiation defect (the Hoxa3,Pax1 compound mutants).

  • The decrease in DP cells is associated with increased apoptosis in both pre-DP and DP cells [ 29 ] . As the defects at the TN to DP transition in these mutants are caused by defective TEC function rather than thymocyte-intrinsic defects, these mice represent an opportunity to study the role of TECs in promoting this transition.

  • The abnormal cell death and proliferation patterns in the Hoxa3,Pax1 compound mutant fetal thymocytes might be caused in part by observed reductions in the transcription levels of the cytokines IL-7 and SCF produced by TECs.


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