Words similar to tecs

Example sentences for: tecs

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Cytokines produced by TECs have been shown to promote proliferation in early stages of thymocyte development, and have been proposed to regulate apoptosis and differentiation, although their precise roles remain controversial [ 23 24 ] . TECs have also been shown to promote thymocyte proliferation in SP cells after selection has occurred [ 15 ] . However, a defined role for TECs at the TN-DP transition remains elusive.
The abnormal cell death and proliferation patterns in the Hoxa3,Pax1 compound mutant fetal thymocytes might be caused in part by observed reductions in the transcription levels of the cytokines IL-7 and SCF produced by TECs.
In order to investigate the regulation of thymocyte development by TECs, we are studying Hoxa3 +/- Pax1 -/-compound mutant mice.
Using semi-quantitative RT-PCR, we analyzed the expression of two cytokines that are produced by TECs, IL-7 and SCF, in pooled, genotype-matched E14.
Cytokines produced by TECs are good candidates for mediating at least some of these changes in thymocyte proliferation and apoptosis in the Hoxa3,Pax1 compound mutants.