Words similar to tbz

Example sentences for: tbz

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Checkpoint rad mutants do not share TBZ Sensitivity
Mutations that disrupt the microtubule cytoskeleton are also known to sensitize cells to TBZ [ 47 ] . However, using anti-tubulin immunofluorescence, we did not discover any gross microtubule cytoskeletal abnormalities in rad26Δ and rad3Δ cells (data not shown).
Alternatively, some structure that is required to prevent TBZ sensitivity, such as centromeric heterochromatin, may function in checkpoint control.
Studies suggest that Hus1, Rad1, and Rad9 function together to form a PCNA-like clamp complex that is loaded onto DNA by Rad17 [ 16 ] . This model predicts that all four proteins should show the same levels of TBZ sensitivity since deletion of any of the four proteins should prevent formation of a functional clamp.
Strains carrying the rad26.T12 mutation undergo cell cycle arrest following treatment with a DNA damage agent, but lose viability upon re-entry into the cell cycle [ 13 40 ] . We found that the rad26.T12 strain is significantly less sensitive to TBZ than rad26Δ and rad3Δ (Figure 2).