Words similar to tbz

Example sentences for: tbz

How can you use “tbz” in a sentence? Here are some example sentences to help you improve your vocabulary:

Mutations that disrupt the microtubule cytoskeleton are also known to sensitize cells to TBZ [ 47 ] . However, using anti-tubulin immunofluorescence, we did not discover any gross microtubule cytoskeletal abnormalities in rad26Δ and rad3Δ cells (data not shown).
The kinase activity of Rad3 is essential for checkpoint signaling and is the only known biochemical function of this 220 kDa protein [ 48 49 ] . The rad3.a strain has an amino acid change (D2230A) in the conserved kinase domain of Rad3 that eliminates cell cycle arrest in response to DNA damaging agents [ 48 49 ] . Interestingly, we found that the rad3.a strain is less sensitive to TBZ than the rad3Δ and rad26Δ strains (Figure 4).
TBZ sensitivity reveals novel aspects of checkpoint Rad protein function
To test whether checkpoint mutants are sensitive to microtubule depolymerization drugs, we spotted serial dilutions of cultures on plates containing 20 mg/ml TBZ.
Next, we tested if the four other checkpoint radΔ alleles ( hus1Δ, rad1Δ, rad9Δ and rad17Δ ) conferred TBZ sensitivity (Figure 3).