Example sentences for: tata

How can you use “tata” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • CC-1065 (Figure 1) is among the most potent antitumor agents discovered [ 9 10 11 12 13 ] . It binds to double-stranded B-DNA within the minor groove with a sequence preference for 5'-d(A/GNTTA)-3' and 5'-d(AAAAA)-3', and alkylates the N3 position of the 3'-adenine with its left-hand CPI segment [ 14 15 ] . CC-1065 also inhibits gene transcription by interfering with binding of the TATA box-binding protein to its target DNA [ 16 ] . Despite its high potency and broad spectrum of antitumor activity, CC-1065 cannot be used in humans because it causes delayed death in experimental animals [ 17 ] . To pursue compounds possessing the potent antitumor activity but devoid of the toxic side effects of the parent compound, many CC-1065 analogues have been synthesized [ 18 19 20 21 22 23 24 25 26 ] .

  • We used the CPD consensus strings for the Drosophila Inr and TATA box, TCA(G/T)T(C/T) and TATAAA, respectively [ 5], permitting up to one mismatch.

  • The C/EBPα-GFP or GFP-C/EBPα expression vectors were transfected into GHFT1-5 cells with a promoter consisting of a single C/EBPα binding site upstream of the growth hormone TATA box.

  • Instead, these 354 motifs were comprised of several variants each of motifs 1-6 and 8 of Table 2; the best variant of motif 1 scored 1,353 and the best variant of the TATA box scored 742.

  • One example is the interleukin-2 (IL-2) promoter, which contains five NFAT binding sites in a region spanning 250 bp upstream of the TATA box [ 29, 30].


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