Words similar to tata
Example sentences for: tata
How can you use “tata” in a sentence? Here are some example sentences to help you improve your vocabulary:
In designing an NFATp-responsive DNA template, we positioned three high-affinity NFAT-binding sites upstream of the adenovirus E1b TATA box and the CAT gene.
The predicted promoter regions are highly GC-rich and lack canonical TATA boxes, suggesting that they may be housekeeping genes [ 39 40 ] .
One example is the interleukin-2 (IL-2) promoter, which contains five NFAT binding sites in a region spanning 250 bp upstream of the TATA box [ 29, 30].
CC-1065 (Figure 1) is among the most potent antitumor agents discovered [ 9 10 11 12 13 ] . It binds to double-stranded B-DNA within the minor groove with a sequence preference for 5'-d(A/GNTTA)-3' and 5'-d(AAAAA)-3', and alkylates the N3 position of the 3'-adenine with its left-hand CPI segment [ 14 15 ] . CC-1065 also inhibits gene transcription by interfering with binding of the TATA box-binding protein to its target DNA [ 16 ] . Despite its high potency and broad spectrum of antitumor activity, CC-1065 cannot be used in humans because it causes delayed death in experimental animals [ 17 ] . To pursue compounds possessing the potent antitumor activity but devoid of the toxic side effects of the parent compound, many CC-1065 analogues have been synthesized [ 18 19 20 21 22 23 24 25 26 ] .
Neither the human nor the mouse gene has a TATA element or CAAT box in the proximal promoter region.